RecName: Full=Src kinase-associated phosphoprotein 2; AltName: Full=Py - Protein

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SKAP2 acts downstream of CD11b/CD18 and regulates neutrophil effector function. [Front Immunol. 2024]
SKAP2 acts downstream of CD11b/CD18 and regulates neutrophil effector function.
Bouti P, Klein BJAM, Verkuijlen PJH, Schornagel K, van Alphen FPJ, Taris KH, van den Biggelaar M, Hoogendijk AJ, van Bruggen R, Kuijpers TW, et al. Front Immunol. 2024; 15:1344761. Epub 2024 Feb 29.
SKAP2 is downregulated in the villous tissues of patients with missed abortion and regulates growth and migration in trophoblasts through the WAVE2-ARP2/3 signaling pathway. [Placenta. 2022]
SKAP2 is downregulated in the villous tissues of patients with missed abortion and regulates growth and migration in trophoblasts through the WAVE2-ARP2/3 signaling pathway.
Jin X, Chen Y, Sheng Z, Wang X, Zhang Z, Huang J, Zhou J, Lin F. Placenta. 2022 Oct; 128:100-111. Epub 2022 Sep 5.
Diabetes With Multiple Autoimmune and Inflammatory Conditions Linked to an Activating SKAP2 Mutation. [Diabetes Care. 2021]
Diabetes With Multiple Autoimmune and Inflammatory Conditions Linked to an Activating SKAP2 Mutation.
Rutsch N, Chamberlain CE, Dixon W, Spector L, Letourneau-Freiberg LR, Lwin WW, Philipson LH, Zarbock A, Saintus K, Wang J, et al. Diabetes Care. 2021 Aug; 44(8):1816-1825. Epub 2021 Jun 25.

RefSeq protein isoforms
See 6 reference sequence protein isoforms for the SKAP2 gene.

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O75563 [Domain Mapping of Disease Mut...]
O75563
Domain Mapping of Disease Mutations
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
Reactome [Reactome]
Reactome
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome

RecName: Full=Src kinase-associated phosphoprotein 2; AltName: Full=Pyk2/RAFTK-a...
RecName: Full=Src kinase-associated phosphoprotein 2; AltName: Full=Pyk2/RAFTK-associated protein; AltName: Full=Retinoic acid-induced protein 70; AltName: Full=SKAP55 homolog; Short=SKAP-55HOM; Short=SKAP-HOM; AltName: Full=Src family-associated phosphoprotein 2; AltName: Full=Src kinase-associated phosphoprotein 55-related protein; AltName: Full=Src-associated adapter protein with PH and SH3 domains
gi|74735515|sp|O75563.1|SKAP2_HUMAN

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