In the absence of ATPase activity, pre-RC formation is blocked prior to MCM2-7 hexamer dimerization.
Evrin C, Fernández-Cid A, Zech J, Herrera MC, Riera A, Clarke P, Brill S, Lurz R, Speck C. Nucleic Acids Res. 2013 Mar 1; 41(5):3162-72. Epub 2013 Feb 1.