RecName: Full=Lymphocyte activation gene 3 protein; Short=LAG-3; AltNa - Protein

Run BLAST
Find regions of similarity between this sequence and other sequences using BLAST.
Identify Conserved Domains
View conserved domains detected in this protein sequence using CD-search.

Indirect suppression of CD4 T cell activation through LAG-3-mediated trans-endocytosis of MHC class II. [Cell Rep. 2024]
Indirect suppression of CD4 T cell activation through LAG-3-mediated trans-endocytosis of MHC class II.
Wakamatsu E, Machiyama H, Toyota H, Takeuchi A, Hashimoto R, Kozono H, Yokosuka T. Cell Rep. 2024 Sep 24; 43(9):114655. Epub 2024 Aug 26.
Start codon variant in LAG3 is associated with decreased LAG-3 expression and increased risk of autoimmune thyroid disease. [Nat Commun. 2024]
Start codon variant in LAG3 is associated with decreased LAG-3 expression and increased risk of autoimmune thyroid disease.
Saevarsdottir S, Bjarnadottir K, Markusson T, Berglund J, Olafsdottir TA, Halldorsson GH, Rutsdottir G, Gunnarsdottir K, Arnthorsson AO, Lund SH, et al. Nat Commun. 2024 Jul 9; 15(1):5748. Epub 2024 Jul 9.
Altered immune co-inhibitory receptor expression and correlation of LAG-3 expression to disease severity in NMOSD. [J Neuroimmunol. 2024]
Altered immune co-inhibitory receptor expression and correlation of LAG-3 expression to disease severity in NMOSD.
Haham N, Zveik O, Rechtman A, Brill L, Vaknin-Dembinsky A. J Neuroimmunol. 2024 Mar 15; 388:578289. Epub 2024 Jan 17.

RefSeq protein isoforms
See 3 reference sequence protein isoforms for the LAG3 gene.

PubMed
PubMed articles cited by protein sequence record
Taxonomy
Taxonomy sequences associated with protein record
BioSystems
BioSystems
CDD Search Results
Display conserved domains within a protein
Conserved Domains (Concise)
Link to a concise list of conserved domains in a protein
Conserved Domains (Full)
Link to conserved domains within a protein
Domain Relatives
Display proteins with similar conserved domain architecture
Full text in PMC
Free full text articles in PMC
Gene
Link to related Genes
OMIM
OMIM records associated with protein sequence
Protein (RefSeq)
Protein gi (UniProtKB) to protein gi (refseq)
PubMed (Weighted)
Links to pubmed
Related Structures (List)
List of related structures

P18627 [Domain Mapping of Disease Mut...]
P18627
Domain Mapping of Disease Mutations
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
Reactome [Reactome]
Reactome
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome
reagent reviews [ExactAntigen/Labome]
reagent reviews
ExactAntigen/Labome

Your browsing activity is empty.

Activity recording is turned off.

Protein