RecName: Full=Protein PML; AltName: Full=E3 SUMO-protein ligase PML; A - Protein

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Mutations at proximal cysteine residues in PML impair ATO binding by destabilizing the RBCC domain. [FEBS J. 2024]
Mutations at proximal cysteine residues in PML impair ATO binding by destabilizing the RBCC domain.
Dubey S, Mishra N, Shelke R, Varma AK. FEBS J. 2024 Apr; 291(7):1422-1438. Epub 2023 Dec 28.
PML-mediated nuclear loosening permits immunomodulation of mesenchymal stem/stromal cells under inflammatory conditions. [Cell Prolif. 2024]
PML-mediated nuclear loosening permits immunomodulation of mesenchymal stem/stromal cells under inflammatory conditions.
Chu Y, Jiang Z, Gong Z, Ji X, Zhu M, Shang Q, Gong P, Cao L, Chen Y, Li P, et al. Cell Prolif. 2024 Apr; 57(4):e13566. Epub 2023 Oct 20.
PML modulates epigenetic composition of chromatin to regulate expression of pro-metastatic genes in triple-negative breast cancer. [Nucleic Acids Res. 2023]
PML modulates epigenetic composition of chromatin to regulate expression of pro-metastatic genes in triple-negative breast cancer.
Fracassi C, Ugge' M, Abdelhalim M, Zapparoli E, Simoni M, Magliulo D, Mazza D, Lazarevic D, Morelli MJ, Collas P, et al. Nucleic Acids Res. 2023 Nov 10; 51(20):11024-11039.

RefSeq genomic sequence
See the genomic reference sequence for the PML gene (NG_029036.1).
RefSeq protein isoforms
See 9 reference sequence protein isoforms for the PML gene.

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P29590 [Domain Mapping of Disease Mut...]
P29590
Domain Mapping of Disease Mutations
Transcript/Protein Information [PANTHER Classification System]
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PANTHER Classification System
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reagents [ExactAntigen/Labome]
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Protein