RecName: Full=Heat shock cognate 71 kDa protein; AltName: Full=Heat sh - Protein

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HSPA8 acts as an amyloidase to suppress necroptosis by inhibiting and reversing functional amyloid formation. [Cell Res. 2023]
HSPA8 acts as an amyloidase to suppress necroptosis by inhibiting and reversing functional amyloid formation.
Wu E, He W, Wu C, Chen Z, Zhou S, Wu X, Hu Z, Jia K, Pan J, Wang L, et al. Cell Res. 2023 Nov; 33(11):851-866. Epub 2023 Aug 14.
An Hspa8 variant is a shocking modifier of spinal muscular atrophy in mice. [Neuron. 2023]
An Hspa8 variant is a shocking modifier of spinal muscular atrophy in mice.
Blatnik AJ 3rd, Macleod Burghes AH. Neuron. 2023 May 3; 111(9):1349-1350.
Inhibition of heat shock protein family A member 8 attenuates spinal cord ischemia-reperfusion injury via astrocyte NF-κB/NLRP3 inflammasome pathway : HSPA8 inhibition protects spinal ischemia-reperfusion injury. [J Neuroinflammation. 2021]
Inhibition of heat shock protein family A member 8 attenuates spinal cord ischemia-reperfusion injury via astrocyte NF-κB/NLRP3 inflammasome pathway : HSPA8 inhibition protects spinal ischemia-reperfusion injury.
Mi J, Yang Y, Yao H, Huan Z, Xu C, Ren Z, Li W, Tang Y, Fu R, Ge X. J Neuroinflammation. 2021 Aug 6; 18(1):170. Epub 2021 Aug 6.

RefSeq protein isoforms
See 2 reference sequence protein isoforms for the Hspa8 gene.

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MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF) [MODBASE, Database of Comparat...]
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF)
Mouse Genome Informatics (MGI) [Mouse Genome Informatics (MGI)]
Mouse Genome Informatics (MGI)
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
Reactome [Reactome]
Reactome
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome
reagent reviews [ExactAntigen/Labome]
reagent reviews
ExactAntigen/Labome
Evolutionary Trace of Functional Site [Evolutionary Trace of Functio...]
Evolutionary Trace of Functional Site

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Protein