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RecName: Full=Cytochrome b; AltName: Full=Complex III subunit 3; AltName: Full=Complex III subunit III; AltName: Full=Cytochrome b-c1 complex subunit 3; AltName: Full=Ubiquinol-cytochrome-c reductase complex cytochrome b subunit

UniProtKB/Swiss-Prot: Q35675.2

Identical Proteins FASTA Graphics 

LOCUS       CYB_PLATE                381 aa            linear   MAM 27-NOV-2024
DEFINITION  RecName: Full=Cytochrome b; AltName: Full=Complex III subunit 3;
            AltName: Full=Complex III subunit III; AltName: Full=Cytochrome
            b-c1 complex subunit 3; AltName: Full=Ubiquinol-cytochrome-c
            reductase complex cytochrome b subunit.
ACCESSION   Q35675
VERSION     Q35675.2
DBSOURCE    UniProtKB: locus CYB_PLATE, accession Q35675;
            class: standard.
            created: Jul 15, 1998.
            sequence updated: Jun 1, 1998.
            annotation updated: Nov 27, 2024.
            xrefs: U07591.1, AAB88767.1
            xrefs (non-sequence databases): AlphaFoldDB:Q35675, SMR:Q35675,
            GO:0005743, GO:0045275, GO:0046872, GO:0008121, GO:0006122,
            CDD:cd00290, CDD:cd00284, FunFam:1.20.810.10:FF:000002,
            InterPro:IPR005798, InterPro:IPR036150, InterPro:IPR005797,
            InterPro:IPR027387, InterPro:IPR030689, InterPro:IPR048260,
            InterPro:IPR048259, InterPro:IPR016174, PANTHER:PTHR19271,
            PANTHER:PTHR19271:SF16, Pfam:PF00032, Pfam:PF00033,
            PIRSF:PIRSF038885, SUPFAM:SSF81648, SUPFAM:SSF81342,
            PROSITE:PS51003, PROSITE:PS51002
KEYWORDS    Electron transport; Heme; Iron; Membrane; Metal-binding;
            Mitochondrion; Mitochondrion inner membrane; Respiratory chain;
            Transmembrane; Transmembrane helix; Transport; Ubiquinone.
SOURCE      mitochondrion Planigale tenuirostris (flat-skulled marsupial mouse)
  ORGANISM  Planigale tenuirostris
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Metatheria; Dasyuromorphia; Dasyuridae; Planigale.
REFERENCE   1  (residues 1 to 381)
  AUTHORS   Krajewski,C., Blacket,M., Buckley,L. and Westerman,M.
  TITLE     A multigene assessment of phylogenetic relationships within the
            dasyurid marsupial subfamily Sminthopsinae
  JOURNAL   Mol Phylogenet Evol 8 (2), 236-248 (1997)
   PUBMED   9299228
  REMARK    NUCLEOTIDE SEQUENCE [GENOMIC DNA].
COMMENT     [FUNCTION] Component of the ubiquinol-cytochrome c reductase
            complex (complex III or cytochrome b-c1 complex) that is part of
            the mitochondrial respiratory chain. The b-c1 complex mediates
            electron transfer from ubiquinol to cytochrome c. Contributes to
            the generation of a proton gradient across the mitochondrial
            membrane that is then used for ATP synthesis.
            {ECO:0000250|UniProtKB:P00157}.
            [COFACTOR] Name=heme b; Xref=ChEBI:CHEBI:60344;
            Evidence={ECO:0000250|UniProtKB:P00157}; Note=Binds 2 heme b groups
            non-covalently. {ECO:0000250|UniProtKB:P00157}.
            [SUBUNIT] The cytochrome bc1 complex contains 11 subunits: 3
            respiratory subunits (MT-CYB, CYC1 and UQCRFS1), 2 core proteins
            (UQCRC1 and UQCRC2) and 6 low-molecular weight proteins
            (UQCRH/QCR6, UQCRB/QCR7, UQCRQ/QCR8, UQCR10/QCR9, UQCR11/QCR10 and
            a cleavage product of UQCRFS1). This cytochrome bc1 complex then
            forms a dimer. {ECO:0000250|UniProtKB:P00157}.
            [SUBCELLULAR LOCATION] Mitochondrion inner membrane
            {ECO:0000250|UniProtKB:P00157}; Multi-pass membrane protein
            {ECO:0000250|UniProtKB:P00157}.
            [MISCELLANEOUS] Heme 1 (or BL or b562) is low-potential and absorbs
            at about 562 nm, and heme 2 (or BH or b566) is high-potential and
            absorbs at about 566 nm. {ECO:0000250}.
            [SIMILARITY] Belongs to the cytochrome b family.
            {ECO:0000255|PROSITE-ProRule:PRU00967,
            ECO:0000255|PROSITE-ProRule:PRU00968}.
            [CAUTION] The full-length protein contains only eight transmembrane
            helices, not nine as predicted by bioinformatics tools.
            {ECO:0000250|UniProtKB:P00157}.
FEATURES             Location/Qualifiers
     source          1..381
                     /organism="Planigale tenuirostris"
                     /organelle="mitochondrion"
                     /db_xref="taxon:32557"
     gene            1..381
                     /gene="MT-CYB"
                     /gene_synonym="COB"
                     /gene_synonym="CYTB"
                     /gene_synonym="MTCYB"
     Protein         1..381
                     /product="Cytochrome b"
                     /note="Complex III subunit 3; Complex III subunit III;
                     Cytochrome b-c1 complex subunit 3; Ubiquinol-cytochrome-c
                     reductase complex cytochrome b subunit"
                     /UniProtKB_evidence="Inferred from homology"
     Region          1..381
                     /region_name="Mature chain"
                     /note="Cytochrome b. /id=PRO_0000061416."
     Region          1..378
                     /region_name="CYTB"
                     /note="cytochrome b; Provisional; MTH00100"
                     /db_xref="CDD:177162"
     Region          33..53
                     /region_name="Transmembrane region"
                     /note="Helical. /evidence=ECO:0000250|UniProtKB:P00157."
     Region          77..98
                     /region_name="Transmembrane region"
                     /note="Helical. /evidence=ECO:0000250|UniProtKB:P00157."
     Region          113..133
                     /region_name="Transmembrane region"
                     /note="Helical. /evidence=ECO:0000250|UniProtKB:P00157."
     Region          178..198
                     /region_name="Transmembrane region"
                     /note="Helical. /evidence=ECO:0000250|UniProtKB:P00157."
     Region          226..246
                     /region_name="Transmembrane region"
                     /note="Helical. /evidence=ECO:0000250|UniProtKB:P00157."
     Region          288..308
                     /region_name="Transmembrane region"
                     /note="Helical. /evidence=ECO:0000250|UniProtKB:P00157."
     Region          320..340
                     /region_name="Transmembrane region"
                     /note="Helical. /evidence=ECO:0000250|UniProtKB:P00157."
     Region          347..367
                     /region_name="Transmembrane region"
                     /note="Helical. /evidence=ECO:0000250|UniProtKB:P00157."
ORIGIN      
        1 mtnlrkthpl mkivnhsfid lpapsnisaw wnfgsllgic lviqiltglf lamhytsdtl
       61 tafssvahic rdvnygwlir nlhangasmf fmclflhvgr giyygsylyk etwnigvill
      121 ltvmatafvg yvlpwgqmsf wgatvitnll saipyvgttl aewiwggfav dkatltrffa
      181 fhfilpfiit alvivhllfl hetgsnnpsg inpdsdkipf hpyytikdal glmfllltll
      241 llalfspdsl gdpdnfspan plntpphikp ewyflfayai lrsipnklgg vlallasili
      301 llvipflhta nqrsmmfrpi sqtlfwilsa nlitltwigg qpveqpfiii gqlasilyfl
      361 lilvlmplag lfenymlkpk w
//
Feature
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