RecName: Full=1-phosphatidylinositol 4,5-bisphosphate phosphodiesteras - Protein

Run BLAST
Find regions of similarity between this sequence and other sequences using BLAST.
Identify Conserved Domains
View conserved domains detected in this protein sequence using CD-search.

Mutations in phospholipase C eta-1 (PLCH1) are associated with holoprosencephaly. [J Med Genet. 2022]
Mutations in phospholipase C eta-1 (PLCH1) are associated with holoprosencephaly.
Drissi I, Fletcher E, Shaheen R, Nahorski M, Alhashem AM, Lisgo S, Fernández-Jaén A, Schon K, Tlili-Graiess K, Smithson SF, et al. J Med Genet. 2022 Apr; 59(4):358-365. Epub 2021 Apr 5.
A canonical EF-loop directs Ca(2+) -sensitivity in phospholipase C-η2. [J Cell Biochem. 2014]
A canonical EF-loop directs Ca(2+) -sensitivity in phospholipase C-η2.
Popovics P, Lu J, Nadia Kamil L, Morgan K, Millar RP, Schmid R, Blindauer CA, Stewart AJ. J Cell Biochem. 2014 Mar; 115(3):557-65.
Association between polymorphisms in COMT, PLCH1, and CYP17A1, and non-small-cell lung cancer risk in Chinese nonsmokers. [Clin Lung Cancer. 2013]
Association between polymorphisms in COMT, PLCH1, and CYP17A1, and non-small-cell lung cancer risk in Chinese nonsmokers.
Zhang Y, Hua S, Zhang A, Kong X, Jiang C, Deng D, Wenlong B. Clin Lung Cancer. 2013 Jan; 14(1):45-9. Epub 2012 Jun 1.

RefSeq protein isoforms
See 34 reference sequence protein isoforms for the PLCH1 gene.

PubMed
PubMed articles cited by protein sequence record
Taxonomy
Taxonomy sequences associated with protein record
BioSystems
BioSystems
CDD Search Results
Display conserved domains within a protein
Conserved Domains (Concise)
Link to a concise list of conserved domains in a protein
Conserved Domains (Full)
Link to conserved domains within a protein
Domain Relatives
Display proteins with similar conserved domain architecture
Full text in PMC
Free full text articles in PMC
Gene
Link to related Genes
OMIM
OMIM records associated with protein sequence
Protein (RefSeq)
Protein gi (UniProtKB) to protein gi (refseq)
PubMed (Weighted)
Links to pubmed
Related Structures (List)
List of related structures

Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
Reactome [Reactome]
Reactome
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome

Your browsing activity is empty.

Activity recording is turned off.

Protein