RecName: Full=Ubiquitin carboxyl-terminal hydrolase 50; AltName: Full= - Protein

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USP50 suppresses alternative RecQ helicase use and deleterious DNA2 activity during replication. [Nat Commun. 2024]
USP50 suppresses alternative RecQ helicase use and deleterious DNA2 activity during replication.
Mackay HL, Stone HR, Ronson GE, Ellis K, Lanz A, Aghabi Y, Walker AK, Starowicz K, Garvin AJ, Van Eijk P, et al. Nat Commun. 2024 Sep 16; 15(1):8102. Epub 2024 Sep 16.
USP50 regulates NLRP3 inflammasome activation in duodenogastric reflux-induced gastric tumorigenesis. [Front Immunol. 2024]
USP50 regulates NLRP3 inflammasome activation in duodenogastric reflux-induced gastric tumorigenesis.
Zhao C, Mu M, Li X, Dong Z, Wang J, Yao C, Zheng J, Sun X, Yu J. Front Immunol. 2024; 15:1326137. Epub 2024 Feb 26.
Induction of deubiquitinating enzyme USP50 during erythropoiesis and its potential role in the regulation of Ku70 stability. [J Investig Med. 2018]
Induction of deubiquitinating enzyme USP50 during erythropoiesis and its potential role in the regulation of Ku70 stability.
Cai J, Wei J, Schrott V, Zhao J, Bullock G, Zhao Y. J Investig Med. 2018 Jan; 66(1):1-6. Epub 2017 Nov 3.

RefSeq protein isoforms
See 2 reference sequence protein isoforms for the USP50 gene.

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Q70EL3 [Domain Mapping of Disease Mut...]
Q70EL3
Domain Mapping of Disease Mutations
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reagents [ExactAntigen/Labome]
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ExactAntigen/Labome

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Protein