RecName: Full=Exopolyphosphatase PRUNE1; AltName: Full=Drosophila-rela - Protein

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PRUNE1 (located on chromosome 1q21.3) promotes multiple myeloma with 1q21 Gain by enhancing the links between purine and mitochondrion. [Br J Haematol. 2023]
PRUNE1 (located on chromosome 1q21.3) promotes multiple myeloma with 1q21 Gain by enhancing the links between purine and mitochondrion.
Xu J, Wang Y, Li P, Chen C, Jiang Z, Wang X, Liu P. Br J Haematol. 2023 Nov; 203(4):599-613. Epub 2023 Sep 4.
Neurodevelopmental disorder with microcephaly, hypotonia, and variable brain anomalies in a consanguineous Iranian family is associated with a homozygous start loss variant in the PRUNE1 gene. [BMC Med Genomics. 2022]
Neurodevelopmental disorder with microcephaly, hypotonia, and variable brain anomalies in a consanguineous Iranian family is associated with a homozygous start loss variant in the PRUNE1 gene.
Gholizadeh MA, Mohammadi-Sarband M, Fardanesh F, Garshasbi M. BMC Med Genomics. 2022 Apr 4; 15(1):78. Epub 2022 Apr 4.
An identical-by-descent novel splice-donor variant in PRUNE1 causes a neurodevelopmental syndrome with prominent dystonia in two consanguineous Sudanese families. [Ann Hum Genet. 2021]
An identical-by-descent novel splice-donor variant in PRUNE1 causes a neurodevelopmental syndrome with prominent dystonia in two consanguineous Sudanese families.
Koko M, Yahia A, Elsayed LE, Hamed AA, Mohammed IN, Elseed MA, Hamad MHA, Babai AM, Siddig RA, Abd Allah ASI, et al. Ann Hum Genet. 2021 Sep; 85(5):186-195. Epub 2021 Jun 10.

RefSeq genomic sequence
See the genomic reference sequence for the PRUNE1 gene (NG_052875.1).
RefSeq protein isoforms
See 14 reference sequence protein isoforms for the PRUNE1 gene.

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Q86TP1 [Domain Mapping of Disease Mut...]
Q86TP1
Domain Mapping of Disease Mutations
Transcript/Protein Information [PANTHER Classification System]
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Protein