RecName: Full=Nucleotide triphosphate diphosphatase NUDT15; AltName: F - Protein

Run BLAST
Find regions of similarity between this sequence and other sequences using BLAST.
Identify Conserved Domains
View conserved domains detected in this protein sequence using CD-search.
Highlight Sequence Features
Opens the Highlight Feature Bar and highlights feature annotations from the FEATURES table of the record. The Highlight Feature Bar can be used to navigate to and highlight other features and provides links to display the highlighted region separately. Links in the FEATURES table will also highlight the corresponding region of the sequence. More...
Find in this Sequence
Finds sub-sequences or patterns in the sequence and highlights the matching regions. The tool works with standard single letter nucleotide or protein codes including ambiguities and can match Prosite patterns in protein sequences. More...

Loss of Nudt15 thiopurine detoxification increases direct DNA damage in hematopoietic stem cells. [Sci Rep. 2023]
Loss of Nudt15 thiopurine detoxification increases direct DNA damage in hematopoietic stem cells.
Yamashita N, Kawahara M, Imai T, Tatsumi G, Asai-Nishishita A, Andoh A. Sci Rep. 2023 Jul 24; 13(1):11908. Epub 2023 Jul 24.
Thiopurine Use During Pregnancy Has Deleterious Effects on Offspring in Nudt15(R138C) Knock-In Mice. [Cell Mol Gastroenterol Hepatol...]
Thiopurine Use During Pregnancy Has Deleterious Effects on Offspring in Nudt15(R138C) Knock-In Mice.
Imai T, Kawahara M, Tatsumi G, Yamashita N, Nishishita-Asai A, Inatomi O, Masamune A, Kakuta Y, Andoh A. Cell Mol Gastroenterol Hepatol. 2021; 12(1):335-337. Epub 2021 Mar 23.
Thiopurine-mediated impairment of hematopoietic stem and leukemia cells in Nudt15(R138C) knock-in mice. [Leukemia. 2020]
Thiopurine-mediated impairment of hematopoietic stem and leukemia cells in Nudt15(R138C) knock-in mice.
Tatsumi G, Kawahara M, Imai T, Nishishita-Asai A, Nishida A, Inatomi O, Yokoyama A, Kakuta Y, Kito K, Andoh A. Leukemia. 2020 Mar; 34(3):882-894. Epub 2019 Oct 24.

RefSeq protein isoforms
See 2 reference sequence protein isoforms for the Nudt15 gene.

PubMed
PubMed articles cited by protein sequence record
Taxonomy
Taxonomy sequences associated with protein record
BioSystems
BioSystems
CDD Search Results
Display conserved domains within a protein
Conserved Domains (Concise)
Link to a concise list of conserved domains in a protein
Conserved Domains (Full)
Link to conserved domains within a protein
Domain Relatives
Display proteins with similar conserved domain architecture
Full text in PMC
Free full text articles in PMC
Gene
Link to related Genes
OMIM
OMIM records associated with protein sequence
Protein (RefSeq)
Protein gi (UniProtKB) to protein gi (refseq)
PubMed (Weighted)
Links to pubmed
Related Structures (List)
List of related structures

Mouse Genome Informatics (MGI) [Mouse Genome Informatics (MGI)]
Mouse Genome Informatics (MGI)
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
Reactome [Reactome]
Reactome
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome

RecName: Full=Nucleotide triphosphate diphosphatase NUDT15; AltName: Full=MutT h...
RecName: Full=Nucleotide triphosphate diphosphatase NUDT15; AltName: Full=MutT homolog 2; Short=mMTH2; AltName: Full=Nucleoside diphosphate-linked moiety X motif 15; Short=Nudix motif 15; AltName: Full=Nucleoside diphosphate-linked to another moiety X hydrolase 15; Short=Nudix hydrolase 15
gi|68565900|sp|Q8BG93.1|NUD15_MOUSE

Protein

Your browsing activity is empty.

Activity recording is turned off.

Protein