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RecName: Full=E3 ubiquitin-protein ligase Fancl; AltName: Full=Fanconi anemia group L protein homolog

UniProtKB/Swiss-Prot: Q8T913.1

GenPept Identical Proteins FASTA

Supplemental Content

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Protein 3D Structure

Crystal Structure of FANCL

PDB: 3K1L

Source: Drosophila melanogaster

Method: X-ray Diffraction

Resolution: 3.2 Å

Articles about the Fancl gene

FANCL replaces BRCA1 as the likely ubiquitin ligase responsible for FANCD2 monoubiquitination. [Cell Cycle. 2004]
FANCL replaces BRCA1 as the likely ubiquitin ligase responsible for FANCD2 monoubiquitination.
Meetei AR, Yan Z, Wang W. Cell Cycle. 2004 Feb; 3(2):179-81.
The structure of the catalytic subunit FANCL of the Fanconi anemia core complex. [Nat Struct Mol Biol. 2010]
The structure of the catalytic subunit FANCL of the Fanconi anemia core complex.
Cole AR, Lewis LP, Walden H. Nat Struct Mol Biol. 2010 Mar; 17(3):294-8. Epub 2010 Feb 14.
Drosophila homologs of FANCD2 and FANCL function in DNA repair. [DNA Repair (Amst). 2006]
Drosophila homologs of FANCD2 and FANCL function in DNA repair.
Marek LR, Bale AE. DNA Repair (Amst). 2006 Nov 8; 5(11):1317-26. Epub 2006 Jul 21.

Reference sequence information

RefSeq protein isoforms
See 2 reference sequence protein isoforms for the Fancl gene.

More about the Fancl gene

Predicted to enable ubiquitin protein ligase activity. Involved in DNA repair and protein monoubiquitination. Predicted to be part of Fancon...
Also Known As: Dmel_CG12812, CG12812, ...

Related information

PubMed
PubMed articles cited by protein sequence record
Taxonomy
Taxonomy sequences associated with protein record
Gene
Link to related Genes
Identical Structures
3D structures for identical protein sequences
Protein (RefSeq)
Protein gi (UniProtKB) to protein gi (refseq)
PubMed (Weighted)
Links to pubmed

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