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RecName: Full=Protein BRICK1; Short=BRK1

UniProtKB/Swiss-Prot: Q8WUW1.1

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Protein 3D Structure

Cryo-EM structure of WAVE regulatory complex with Rac1 bound on both A and D site

PDB: 7USE

Source: Homo sapiens

Method: Electron Microscopy

Resolution: 3 Å

See all 5 structures...

Articles about the BRK1 gene

Sp1 transcriptionally regulates BRK1 expression in non-small cell lung cancer cells. [Gene. 2014]
Sp1 transcriptionally regulates BRK1 expression in non-small cell lung cancer cells.
Li M, Ling B, Xiao T, Tan J, An N, Han N, Guo S, Cheng S, Zhang K. Gene. 2014 Jun 1; 542(2):134-40. Epub 2014 Mar 25.
Metastatic potential of lung squamous cell carcinoma associated with HSPC300 through its interaction with WAVE2. [Lung Cancer. 2009]
Metastatic potential of lung squamous cell carcinoma associated with HSPC300 through its interaction with WAVE2.
Cai X, Xiao T, James SY, Da J, Lin D, Liu Y, Zheng Y, Zou S, Di X, Guo S, et al. Lung Cancer. 2009 Sep; 65(3):299-305. Epub 2009 Jul 2.
Purification and architecture of the ubiquitous Wave complex. [Proc Natl Acad Sci U S A. 2004]
Purification and architecture of the ubiquitous Wave complex.
Gautreau A, Ho HY, Li J, Steen H, Gygi SP, Kirschner MW. Proc Natl Acad Sci U S A. 2004 Mar 30; 101(13):4379-83. Epub 2004 Mar 19.

Reference sequence information

RefSeq protein
See the reference protein sequence for protein BRICK1 (NP_060932.2).

More about the BRK1 gene

Enables identical protein binding activity. Contributes to small GTPase binding activity. Involved in Rac protein signal transduction and po...
Also Known As: C3orf10, HSPC300, MDS02...

Related information

PubMed
PubMed articles cited by protein sequence record
Taxonomy
Taxonomy sequences associated with protein record
BioSystems
BioSystems
Full text in PMC
Free full text articles in PMC
Gene
Link to related Genes
Identical Structures
3D structures for identical protein sequences
OMIM
OMIM records associated with protein sequence
Protein (RefSeq)
Protein gi (UniProtKB) to protein gi (refseq)
PubMed (Weighted)
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LinkOut to external resources

Q8WUW1 [Domain Mapping of Disease Mut...]
Q8WUW1
Domain Mapping of Disease Mutations
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
Reactome [Reactome]
Reactome
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome

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