RecName: Full=Bifunctional purine biosynthesis protein ATIC; AltName: - Protein

Run BLAST
Find regions of similarity between this sequence and other sequences using BLAST.
Identify Conserved Domains
View conserved domains detected in this protein sequence using CD-search.

AMPK Activation via Modulation of De Novo Purine Biosynthesis with an Inhibitor of ATIC Homodimerization. [Chem Biol. 2015]
AMPK Activation via Modulation of De Novo Purine Biosynthesis with an Inhibitor of ATIC Homodimerization.
Asby DJ, Cuda F, Beyaert M, Houghton FD, Cagampang FR, Tavassoli A. Chem Biol. 2015 Jul 23; 22(7):838-48. Epub 2015 Jul 2.
5-Aminoimidazole-4-carboxamide ribonucleotide formyltransferase/inosine monophosphate cyclohydrolase promotes pulmonary arterial smooth muscle cell proliferation via the Ras signaling pathway. [Am J Physiol Cell Physiol. 2024]
5-Aminoimidazole-4-carboxamide ribonucleotide formyltransferase/inosine monophosphate cyclohydrolase promotes pulmonary arterial smooth muscle cell proliferation via the Ras signaling pathway.
Shi X, Ma Q, Huo Y, Su Y. Am J Physiol Cell Physiol. 2024 Oct 1; 327(4):C901-C912. Epub 2024 Aug 12.
Purine synthesis suppression reduces the development and progression of pulmonary hypertension in rodent models. [Eur Heart J. 2023]
Purine synthesis suppression reduces the development and progression of pulmonary hypertension in rodent models.
Ma Q, Yang Q, Xu J, Sellers HG, Brown ZL, Liu Z, Bordan Z, Shi X, Zhao D, Cai Y, et al. Eur Heart J. 2023 Apr 7; 44(14):1265-1279.

RefSeq protein
See the reference protein sequence for bifunctional purine biosynthesis protein ATIC (NP_080471.2).

PubMed
PubMed articles cited by protein sequence record
Taxonomy
Taxonomy sequences associated with protein record
BioAssay by Target (Summary)
BioAssay by Target (Summary)
BioSystems
BioSystems
CDD Search Results
Display conserved domains within a protein
Conserved Domains (Concise)
Link to a concise list of conserved domains in a protein
Conserved Domains (Full)
Link to conserved domains within a protein
Domain Relatives
Display proteins with similar conserved domain architecture
Full text in PMC
Free full text articles in PMC
Gene
Link to related Genes
Protein (RefSeq)
Protein gi (UniProtKB) to protein gi (refseq)
PubMed (Weighted)
Links to pubmed
Related Structures (List)
List of related structures

Mouse Genome Informatics (MGI) [Mouse Genome Informatics (MGI)]
Mouse Genome Informatics (MGI)
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
Reactome [Reactome]
Reactome
reagent reviews [ExactAntigen/Labome]
reagent reviews
ExactAntigen/Labome
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome

Your browsing activity is empty.

Activity recording is turned off.

Protein