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RecName: Full=DNA-directed RNA polymerases I, II, and III subunit RPABC5; Short=RNA polymerases I, II, and III subunit ABC5

UniProtKB/Swiss-Prot: Q9GR61.1

Identical Proteins FASTA Graphics 

LOCUS       RPAB5_CAEEL               67 aa            linear   INV 27-NOV-2024
DEFINITION  RecName: Full=DNA-directed RNA polymerases I, II, and III subunit
            RPABC5; Short=RNA polymerases I, II, and III subunit ABC5.
ACCESSION   Q9GR61
VERSION     Q9GR61.1
DBSOURCE    UniProtKB: locus RPAB5_CAEEL, accession Q9GR61;
            class: standard.
            created: Aug 31, 2004.
            sequence updated: Mar 1, 2001.
            annotation updated: Nov 27, 2024.
            xrefs: FO081769.2, CCD73423.1, NP_490923.1
            xrefs (non-sequence databases): AlphaFoldDB:Q9GR61, SMR:Q9GR61,
            BioGRID:37250, ComplexPortal:CPX-2812, ComplexPortal:CPX-8913,
            STRING:6239.Y37E3.3.1, PaxDb:6239-Y37E3.3, PeptideAtlas:Q9GR61,
            EnsemblMetazoa:Y37E3.3.1, EnsemblMetazoa:Y37E3.3.1,
            EnsemblMetazoa:WBGene00021347, GeneID:171763,
            KEGG:cel:CELE_Y37E3.3, AGR:WB:WBGene00021347, CTD:171763,
            WormBase:Y37E3.3, WormBase:CE26662, eggNOG:KOG3497,
            GeneTree:ENSGT00390000007087, HOGENOM:CLU_143122_1_1_1,
            InParanoid:Q9GR61, OMA:KYCCRRM, OrthoDB:257at2759,
            PhylomeDB:Q9GR61, Reactome:R-CEL-112382, Reactome:R-CEL-113418,
            Reactome:R-CEL-5250924, Reactome:R-CEL-5578749,
            Reactome:R-CEL-674695, Reactome:R-CEL-6781823,
            Reactome:R-CEL-6782135, Reactome:R-CEL-6782210,
            Reactome:R-CEL-6796648, Reactome:R-CEL-6803529,
            Reactome:R-CEL-6807505, Reactome:R-CEL-72086, Reactome:R-CEL-72163,
            Reactome:R-CEL-72165, Reactome:R-CEL-72203, Reactome:R-CEL-73762,
            Reactome:R-CEL-73772, Reactome:R-CEL-73776, Reactome:R-CEL-73779,
            Reactome:R-CEL-75953, Reactome:R-CEL-75955, Reactome:R-CEL-76042,
            Reactome:R-CEL-77075, Reactome:R-CEL-9018519, PRO:PR:Q9GR61,
            Proteomes:UP000001940, Bgee:WBGene00021347, GO:0005736, GO:0005665,
            GO:0005666, GO:0003677, GO:0003899, GO:0008270, GO:0006360,
            GO:0006366, GO:0042797, FunFam:1.10.10.60:FF:000024,
            Gene3D:1.10.10.60, HAMAP:MF_00250, InterPro:IPR023580,
            InterPro:IPR020789, InterPro:IPR000268, PANTHER:PTHR23431:SF3,
            PANTHER:PTHR23431, Pfam:PF01194, PIRSF:PIRSF005653,
            SUPFAM:SSF46924, PROSITE:PS01112
KEYWORDS    DNA-directed RNA polymerase; Metal-binding; Nucleus; Reference
            proteome; Transcription; Zinc.
SOURCE      Caenorhabditis elegans
  ORGANISM  Caenorhabditis elegans
            Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
            Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
            Caenorhabditis.
REFERENCE   1  (residues 1 to 67)
  CONSRTM   C. elegans Sequencing Consortium
  TITLE     Genome sequence of the nematode C. elegans: a platform for
            investigating biology
  JOURNAL   Science 282 (5396), 2012-2018 (1998)
   PUBMED   9851916
  REMARK    NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].;
            STRAIN=Bristol N2
            Erratum:[Science 1999 Jan 1;283(5398):35]
COMMENT     [FUNCTION] DNA-dependent RNA polymerase catalyzes the transcription
            of DNA into RNA using the four ribonucleoside triphosphates as
            substrates. Common component of RNA polymerases I, II and III which
            synthesize ribosomal RNA precursors, mRNA precursors and many
            functional non-coding RNAs, and a small RNAs, such as 5S rRNA and
            tRNAs, respectively. Pol II is the central component of the basal
            RNA polymerase II transcription machinery. Pols are composed of
            mobile elements that move relative to each other. In Pol II, RBP10
            is part of the core element with the central large cleft (By
            similarity). {ECO:0000250}.
            [SUBUNIT] Component of the RNA polymerase I (Pol I), RNA polymerase
            II (Pol II) and RNA polymerase III (Pol III) complexes consisting
            of at least 13, 12 and 17 subunits, respectively. {ECO:0000250}.
            [SUBCELLULAR LOCATION] Nucleus {ECO:0000250}.
            [SIMILARITY] Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA
            polymerase subunit family. {ECO:0000305}.
FEATURES             Location/Qualifiers
     source          1..67
                     /organism="Caenorhabditis elegans"
                     /db_xref="taxon:6239"
     gene            1..67
                     /gene="rpb-10"
                     /locus_tag="Y37E3.3"
     Protein         1..67
                     /product="DNA-directed RNA polymerases I, II, and III
                     subunit RPABC5"
                     /note="RNA polymerases I, II, and III subunit ABC5"
                     /UniProtKB_evidence="Inferred from homology"
     Region          1..67
                     /region_name="PLN00032"
                     /note="DNA-directed RNA polymerase; Provisional"
                     /db_xref="CDD:215034"
     Region          1..67
                     /region_name="Mature chain"
                     /note="DNA-directed RNA polymerases I, II, and III subunit
                     RPABC5. /id=PRO_0000121335."
ORIGIN      
        1 miipircftc gkvigdkwet ylgflqseys egdaldalgl rryccrrmll ahvdliekll
       61 nyhplek
//
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