LOCUS RPAB5_CAEEL 67 aa linear INV 27-NOV-2024
DEFINITION RecName: Full=DNA-directed RNA polymerases I, II, and III subunit
RPABC5; Short=RNA polymerases I, II, and III subunit ABC5.
ACCESSION Q9GR61
VERSION Q9GR61.1
DBSOURCE UniProtKB: locus RPAB5_CAEEL, accession Q9GR61;
class: standard.
created: Aug 31, 2004.
sequence updated: Mar 1, 2001.
annotation updated: Nov 27, 2024.
xrefs: FO081769.2, CCD73423.1, NP_490923.1
xrefs (non-sequence databases): AlphaFoldDB:Q9GR61, SMR:Q9GR61,
BioGRID:37250, ComplexPortal:CPX-2812, ComplexPortal:CPX-8913,
STRING:6239.Y37E3.3.1, PaxDb:6239-Y37E3.3, PeptideAtlas:Q9GR61,
EnsemblMetazoa:Y37E3.3.1, EnsemblMetazoa:Y37E3.3.1,
EnsemblMetazoa:WBGene00021347, GeneID:171763,
KEGG:cel:CELE_Y37E3.3, AGR:WB:WBGene00021347, CTD:171763,
WormBase:Y37E3.3, WormBase:CE26662, eggNOG:KOG3497,
GeneTree:ENSGT00390000007087, HOGENOM:CLU_143122_1_1_1,
InParanoid:Q9GR61, OMA:KYCCRRM, OrthoDB:257at2759,
PhylomeDB:Q9GR61, Reactome:R-CEL-112382, Reactome:R-CEL-113418,
Reactome:R-CEL-5250924, Reactome:R-CEL-5578749,
Reactome:R-CEL-674695, Reactome:R-CEL-6781823,
Reactome:R-CEL-6782135, Reactome:R-CEL-6782210,
Reactome:R-CEL-6796648, Reactome:R-CEL-6803529,
Reactome:R-CEL-6807505, Reactome:R-CEL-72086, Reactome:R-CEL-72163,
Reactome:R-CEL-72165, Reactome:R-CEL-72203, Reactome:R-CEL-73762,
Reactome:R-CEL-73772, Reactome:R-CEL-73776, Reactome:R-CEL-73779,
Reactome:R-CEL-75953, Reactome:R-CEL-75955, Reactome:R-CEL-76042,
Reactome:R-CEL-77075, Reactome:R-CEL-9018519, PRO:PR:Q9GR61,
Proteomes:UP000001940, Bgee:WBGene00021347, GO:0005736, GO:0005665,
GO:0005666, GO:0003677, GO:0003899, GO:0008270, GO:0006360,
GO:0006366, GO:0042797, FunFam:1.10.10.60:FF:000024,
Gene3D:1.10.10.60, HAMAP:MF_00250, InterPro:IPR023580,
InterPro:IPR020789, InterPro:IPR000268, PANTHER:PTHR23431:SF3,
PANTHER:PTHR23431, Pfam:PF01194, PIRSF:PIRSF005653,
SUPFAM:SSF46924, PROSITE:PS01112
KEYWORDS DNA-directed RNA polymerase; Metal-binding; Nucleus; Reference
proteome; Transcription; Zinc.
SOURCE Caenorhabditis elegans
ORGANISM Caenorhabditis elegans
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
Caenorhabditis.
REFERENCE 1 (residues 1 to 67)
CONSRTM C. elegans Sequencing Consortium
TITLE Genome sequence of the nematode C. elegans: a platform for
investigating biology
JOURNAL Science 282 (5396), 2012-2018 (1998)
PUBMED 9851916
REMARK NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].;
STRAIN=Bristol N2
Erratum:[Science 1999 Jan 1;283(5398):35]
COMMENT [FUNCTION] DNA-dependent RNA polymerase catalyzes the transcription
of DNA into RNA using the four ribonucleoside triphosphates as
substrates. Common component of RNA polymerases I, II and III which
synthesize ribosomal RNA precursors, mRNA precursors and many
functional non-coding RNAs, and a small RNAs, such as 5S rRNA and
tRNAs, respectively. Pol II is the central component of the basal
RNA polymerase II transcription machinery. Pols are composed of
mobile elements that move relative to each other. In Pol II, RBP10
is part of the core element with the central large cleft (By
similarity). {ECO:0000250}.
[SUBUNIT] Component of the RNA polymerase I (Pol I), RNA polymerase
II (Pol II) and RNA polymerase III (Pol III) complexes consisting
of at least 13, 12 and 17 subunits, respectively. {ECO:0000250}.
[SUBCELLULAR LOCATION] Nucleus {ECO:0000250}.
[SIMILARITY] Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA
polymerase subunit family. {ECO:0000305}.
FEATURES Location/Qualifiers
source 1..67
/organism="Caenorhabditis elegans"
/db_xref="taxon:6239"
gene 1..67
/gene="rpb-10"
/locus_tag="Y37E3.3"
Protein 1..67
/product="DNA-directed RNA polymerases I, II, and III
subunit RPABC5"
/note="RNA polymerases I, II, and III subunit ABC5"
/UniProtKB_evidence="Inferred from homology"
Region 1..67
/region_name="PLN00032"
/note="DNA-directed RNA polymerase; Provisional"
/db_xref="CDD:215034"
Region 1..67
/region_name="Mature chain"
/note="DNA-directed RNA polymerases I, II, and III subunit
RPABC5. /id=PRO_0000121335."
ORIGIN
1 miipircftc gkvigdkwet ylgflqseys egdaldalgl rryccrrmll ahvdliekll
61 nyhplek
//