RecName: Full=Serine/threonine-protein kinase TBK1; AltName: Full=NF-k - Protein

Run BLAST
Find regions of similarity between this sequence and other sequences using BLAST.
Identify Conserved Domains
View conserved domains detected in this protein sequence using CD-search.

The Ca(2+)-dependent phosphatase calcineurin dephosphorylates TBK1 to suppress antiviral innate immunity. [J Virol. 2024]
The Ca(2+)-dependent phosphatase calcineurin dephosphorylates TBK1 to suppress antiviral innate immunity.
Qu Y, Wang S, Jiang H, Wang Q, Liao Y, Qiu X, Tan L, Song C, Ding C, Sun Y, et al. J Virol. 2024 May 14; 98(5):e0001624. Epub 2024 Apr 2.
An Updated Evolutionary and Structural Study of TBK1 Reveals Highly Conserved Motifs as Potential Pharmacological Targets in Neurodegenerative Diseases. [Adv Exp Med Biol. 2023]
An Updated Evolutionary and Structural Study of TBK1 Reveals Highly Conserved Motifs as Potential Pharmacological Targets in Neurodegenerative Diseases.
Papageorgiou L, Mangana E, Papakonstantinou E, Diakou I, Pierouli K, Dragoumani K, Bacopoulou F, Chrousos GP, Exarchos TP, Vlamos P, et al. Adv Exp Med Biol. 2023; 1423:41-57.
TBK1 variants in Chinese patients with amyotrophic lateral sclerosis: Genetic analysis and clinical features. [Eur J Neurol. 2023]
TBK1 variants in Chinese patients with amyotrophic lateral sclerosis: Genetic analysis and clinical features.
Zhao B, Jiang Q, Lin J, Wei Q, Li C, Hou Y, Cao B, Zhang L, Ou R, Liu K, et al. Eur J Neurol. 2023 Oct; 30(10):3079-3089. Epub 2023 Jul 18.

RefSeq genomic sequence
See the genomic reference sequence for the TBK1 gene (NG_046906.1).
RefSeq protein isoforms
See 5 reference sequence protein isoforms for the TBK1 gene.

PubMed
PubMed articles cited by protein sequence record
Taxonomy
Taxonomy sequences associated with protein record
BioAssay by Target (Summary)
BioAssay by Target (Summary)
BioSystems
BioSystems
CDD Search Results
Display conserved domains within a protein
Conserved Domains (Concise)
Link to a concise list of conserved domains in a protein
Conserved Domains (Full)
Link to conserved domains within a protein
Domain Relatives
Display proteins with similar conserved domain architecture
Full text in PMC
Free full text articles in PMC
Gene
Link to related Genes
Identical Structures
3D structures for identical protein sequences
OMIM
OMIM records associated with protein sequence
Protein (RefSeq)
Protein gi (UniProtKB) to protein gi (refseq)
PubMed (Weighted)
Links to pubmed
Related Structures (List)
List of related structures

Q9UHD2 [Domain Mapping of Disease Mut...]
Q9UHD2
Domain Mapping of Disease Mutations
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
Reactome [Reactome]
Reactome
reagent reviews [ExactAntigen/Labome]
reagent reviews
ExactAntigen/Labome
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome

Your browsing activity is empty.

Activity recording is turned off.

Protein