RecName: Full=TRPM8 channel-associated factor 1; AltName: Full=TRP cha - Protein

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TCAF1 promotes TRPV2-mediated Ca(2+) release in response to cytosolic DNA to protect stressed replication forks. [Nat Commun. 2024]
TCAF1 promotes TRPV2-mediated Ca(2+) release in response to cytosolic DNA to protect stressed replication forks.
Kong L, Cheng C, Cheruiyot A, Yuan J, Yang Y, Hwang S, Foust D, Tsao N, Wilkerson E, Mosammaparast N, et al. Nat Commun. 2024 May 30; 15(1):4609. Epub 2024 May 30.
Evidence for opposing selective forces operating on human-specific duplicated TCAF genes in Neanderthals and humans. [Nat Commun. 2021]
Evidence for opposing selective forces operating on human-specific duplicated TCAF genes in Neanderthals and humans.
Hsieh P, Dang V, Vollger MR, Mao Y, Huang TH, Dishuck PC, Baker C, Cantsilieris S, Lewis AP, Munson KM, et al. Nat Commun. 2021 Aug 25; 12(1):5118. Epub 2021 Aug 25.
Secreted retrovirus-like GAG-domain-containing protein PEG10 is regulated by UBE3A and is involved in Angelman syndrome pathophysiology. [Cell Rep Med. 2021]
Secreted retrovirus-like GAG-domain-containing protein PEG10 is regulated by UBE3A and is involved in Angelman syndrome pathophysiology.
Pandya NJ, Wang C, Costa V, Lopatta P, Meier S, Zampeta FI, Punt AM, Mientjes E, Grossen P, Distler T, et al. Cell Rep Med. 2021 Aug 17; 2(8):100360. Epub 2021 Aug 17.

RefSeq protein isoforms
See 15 reference sequence protein isoforms for the TCAF1 gene.

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Transcript/Protein Information [PANTHER Classification System]
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Protein