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NCBI Reference Sequence: WP_004118488.1
Identical Proteins FASTA Graphics
Download a prokaryotic data package including protein sequence and gene sequence for all annotated locations for this protein as a zip archive.
LOCUS WP_004118488 83 aa linear BCT 15-JUL-2024 DEFINITION MULTISPECIES: type II toxin-antitoxin system Phd/YefM family antitoxin [Enterobacterales]. ACCESSION WP_004118488 VERSION WP_004118488.1 KEYWORDS RefSeq. SOURCE Enterobacterales ORGANISM Enterobacterales Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria. REFERENCE 1 (residues 1 to 83) AUTHORS Garcia-Pino,A., De Gieter,S., Talavera,A., De Greve,H., Efremov,R.G. and Loris,R. TITLE An intrinsically disordered entropic switch determines allostery in Phd-Doc regulation JOURNAL Nat Chem Biol 12 (7), 490-496 (2016) PUBMED 27159580 REFERENCE 2 (residues 1 to 83) AUTHORS Garcia-Pino,A., Christensen-Dalsgaard,M., Wyns,L., Yarmolinsky,M., Magnuson,R.D., Gerdes,K. and Loris,R. TITLE Doc of prophage P1 is inhibited by its antitoxin partner Phd through fold complementation JOURNAL J Biol Chem 283 (45), 30821-30827 (2008) PUBMED 18757857 REFERENCE 3 (residues 1 to 83) AUTHORS Magnuson,R. and Yarmolinsky,M.B. TITLE Corepression of the P1 addiction operon by Phd and Doc JOURNAL J Bacteriol 180 (23), 6342-6351 (1998) PUBMED 9829946 COMMENT REFSEQ: This record represents a single, non-redundant, protein sequence which may be annotated on many different RefSeq genomes from the same, or different, species. ##Evidence-For-Name-Assignment-START## Evidence Category :: Conserved Domain (CDD) Evidence Accession :: Domain architecture ID 10005482 Evidence Source :: NCBI SPARCLE ##Evidence-For-Name-Assignment-END## COMPLETENESS: full length. FEATURES Location/Qualifiers source 1..83 /organism="Enterobacterales" /db_xref="taxon:91347" Protein 1..83 /product="type II toxin-antitoxin system Phd/YefM family antitoxin" /GO_component="GO:0110001 - toxin-antitoxin complex [Evidence IEA]" /GO_function="GO:0003677 - DNA binding [Evidence IEA]; GO:0097351 - toxin sequestering activity [Evidence IEA]" /GO_process="GO:0045927 - positive regulation of growth [Evidence IEA]; GO:0006355 - regulation of DNA-templated transcription [Evidence IEA]" /calculated_mol_wt=9094 Region 10..76 /region_name="StbD" /note="Antitoxin component YafN of the YafNO toxin-antitoxin module, PHD/YefM family [Defense mechanisms]; COG2161" /db_xref="CDD:441764" ORIGIN 1 mtniilcdvt asiselkndp vatasagggy pvaiidrnrp vfycvpaaly eqmldaldek 61 dlvqliterq nqplrevdln qyl //
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Conserved Domains
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