LOCUS WP_023303988 321 aa linear BCT 23-DEC-2024
DEFINITION MULTISPECIES: GDP-L-fucose synthase family protein [Enterobacter].
ACCESSION WP_023303988
VERSION WP_023303988.1
KEYWORDS RefSeq.
SOURCE Enterobacter
ORGANISM Enterobacter
Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
Enterobacterales; Enterobacteriaceae.
REFERENCE 1 (residues 1 to 321)
AUTHORS Kallberg,Y., Oppermann,U. and Persson,B.
TITLE Classification of the short-chain dehydrogenase/reductase
superfamily using hidden Markov models
JOURNAL FEBS J 277 (10), 2375-2386 (2010)
PUBMED 20423462
REFERENCE 2 (residues 1 to 321)
AUTHORS Persson,B., Kallberg,Y., Bray,J.E., Bruford,E., Dellaporta,S.L.,
Favia,A.D., Duarte,R.G., Jornvall,H., Kavanagh,K.L., Kedishvili,N.,
Kisiela,M., Maser,E., Mindnich,R., Orchard,S., Penning,T.M.,
Thornton,J.M., Adamski,J. and Oppermann,U.
TITLE The SDR (short-chain dehydrogenase/reductase and related enzymes)
nomenclature initiative
JOURNAL Chem Biol Interact 178 (1-3), 94-98 (2009)
PUBMED 19027726
REFERENCE 3 (residues 1 to 321)
AUTHORS Kavanagh,K.L., Jornvall,H., Persson,B. and Oppermann,U.
TITLE Medium- and short-chain dehydrogenase/reductase gene and protein
families : the SDR superfamily: functional and structural diversity
within a family of metabolic and regulatory enzymes
JOURNAL Cell Mol Life Sci 65 (24), 3895-3906 (2008)
PUBMED 19011750
REFERENCE 4 (residues 1 to 321)
AUTHORS Ladenstein,R., Winberg,J.O. and Benach,J.
TITLE Medium- and short-chain dehydrogenase/reductase gene and protein
families : Structure-function relationships in short-chain alcohol
dehydrogenases
JOURNAL Cell Mol Life Sci 65 (24), 3918-3935 (2008)
PUBMED 19011748
REFERENCE 5 (residues 1 to 321)
AUTHORS Oppermann,U., Filling,C., Hult,M., Shafqat,N., Wu,X., Lindh,M.,
Shafqat,J., Nordling,E., Kallberg,Y., Persson,B. and Jornvall,H.
TITLE Short-chain dehydrogenases/reductases (SDR): the 2002 update
JOURNAL Chem Biol Interact 143-144, 247-253 (2003)
PUBMED 12604210
COMMENT REFSEQ: This record represents a single, non-redundant, protein
sequence which may be annotated on many different RefSeq genomes
from the same, or different, species.
##Evidence-For-Name-Assignment-START##
Evidence Category :: Conserved Domain (CDD)
Evidence Accession :: Domain architecture ID 10142801
Evidence Source :: NCBI SPARCLE
##Evidence-For-Name-Assignment-END##
COMPLETENESS: full length.
FEATURES Location/Qualifiers
source 1..321
/organism="Enterobacter"
/db_xref="taxon:547"
Protein 1..321
/product="GDP-L-fucose synthase family protein"
/EC_number="1.1.1.-"
/GO_function="GO:0016491 - oxidoreductase activity
[Evidence IEA]"
/calculated_mol_wt=36140
Region 5..313
/region_name="GDP_FS_SDR_e"
/note="GDP-fucose synthetase, extended (e) SDRs; cd05239"
/db_xref="CDD:187550"
Site order(10,12..15,36,39..42,62..64,66,86,105..107,136,140,
163..164,166)
/site_type="other"
/note="NADP binding site [chemical binding]"
/db_xref="CDD:187550"
Site order(83,107,136,140)
/site_type="active"
/db_xref="CDD:187550"
Site order(107,136,165,184,201,209)
/site_type="other"
/note="putative substrate binding site [chemical binding]"
/db_xref="CDD:187550"
ORIGIN
1 mtkqrifvag hrgmvgsaiv rqleqrgdve vivrtrdeln lldskavqdf faseridqvy
61 laaakvggiv anntypadfi yenmmiesni ihaahlynvn kllflgssci ypkmakqpia
121 esellqgtle atnepyaiak iagiklcesy nrqynrdyrs vmptnlygph dnfhpsnshv
181 ipallrrfhe ataenapdvv vwgsgtpmre flhvddmaaa sihvmeldre vwqentepml
241 shinvgtgvd ctirelaqti aqvvgykgrv vfdatkpdgt prklldvtrl hqlgwyhevs
301 leqglastyq wflenqhrfr g
//