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NCBI Reference Sequence: WP_276836072.1
Identical Proteins FASTA Graphics
Download a prokaryotic data package including protein sequence and gene sequence for all annotated locations for this protein as a zip archive.
LOCUS WP_276836072 787 aa linear BCT 19-NOV-2024 DEFINITION endonuclease MutS2 [Megasphaera stantonii]. ACCESSION WP_276836072 VERSION WP_276836072.1 KEYWORDS RefSeq. SOURCE Megasphaera stantonii ORGANISM Megasphaera stantonii Bacteria; Bacillati; Bacillota; Negativicutes; Veillonellales; Veillonellaceae; Megasphaera. REFERENCE 1 (residues 1 to 787) AUTHORS Jeong,E., Jo,H., Kim,T.G. and Ban,C. TITLE Characterization of multi-functional properties and conformational analysis of MutS2 from Thermotoga maritima MSB8 JOURNAL PLoS One 7 (4), e34529 (2012) PUBMED 22545085 REFERENCE 2 (residues 1 to 787) AUTHORS Fukui,K., Nakagawa,N., Kitamura,Y., Nishida,Y., Masui,R. and Kuramitsu,S. TITLE Crystal structure of MutS2 endonuclease domain and the mechanism of homologous recombination suppression JOURNAL J Biol Chem 283 (48), 33417-33427 (2008) PUBMED 18838375 REFERENCE 3 (residues 1 to 787) AUTHORS Kang,J., Huang,S. and Blaser,M.J. TITLE Structural and functional divergence of MutS2 from bacterial MutS1 and eukaryotic MSH4-MSH5 homologs JOURNAL J Bacteriol 187 (10), 3528-3537 (2005) PUBMED 15866941 REFERENCE 4 (residues 1 to 787) AUTHORS Pinto,A.V., Mathieu,A., Marsin,S., Veaute,X., Ielpi,L., Labigne,A. and Radicella,J.P. TITLE Suppression of homologous and homeologous recombination by the bacterial MutS2 protein JOURNAL Mol Cell 17 (1), 113-120 (2005) PUBMED 15629722 REFERENCE 5 (residues 1 to 787) AUTHORS Eisen,J.A. TITLE A phylogenomic study of the MutS family of proteins JOURNAL Nucleic Acids Res 26 (18), 4291-4300 (1998) PUBMED 9722651 COMMENT REFSEQ: This record represents a single, non-redundant, protein sequence which may be annotated on many different RefSeq genomes from the same, or different, species. ##Evidence-For-Name-Assignment-START## Evidence Category :: HMM Evidence Accession :: TIGR01069.2 Evidence Source :: JCVI ##Evidence-For-Name-Assignment-END## COMPLETENESS: full length. FEATURES Location/Qualifiers source 1..787 /organism="Megasphaera stantonii" /db_xref="taxon:2144175" Protein 1..787 /product="endonuclease MutS2" /GO_function="GO:0016887 - ATP hydrolysis activity [Evidence IEA]; GO:0004519 - endonuclease activity [Evidence IEA]; GO:0030983 - mismatched DNA binding [Evidence IEA]" /GO_process="GO:0006259 - DNA metabolic process [Evidence IEA]; GO:0045910 - negative regulation of DNA recombination [Evidence IEA]" /calculated_mol_wt=88231 Region 1..787 /region_name="MutS2" /note="dsDNA-specific endonuclease/ATPase MutS2 [Replication, recombination and repair]; COG1193" /db_xref="CDD:440806" ORIGIN 1 mnkrslrilg fyqvqnmlir lapsrmskei arrlkpvcda eevarslndt eeayrclqse 61 asvpmggivd irpalekarr dvtlegqdci diwnnvrryg dirqyfmdkg eeypqlaeka 121 egigdfslis hkmagvfdqn hqirdnaspe lmrlrnrive lerqtkryvt gvlqnkeyqk 181 yfqdalvtvr nnryvvpikq eyrhafpgiv hdtsasgstl yieplaivna nndlqaarig 241 etkeierifr rltalvsgqy ddlmdstkcv aaleftfaka qlaqqmkacr pavspkgivr 301 lvqarhplid akavvpntii lggeyrilli tgsntggktv smktlgllvl mhqaglfipv 361 gedselpifr dvfsdigdeq disqnlstfs shmkqlvyil rhctaddlil adelgsgtdp 421 aegsaiaiav ldalyrkgay vmvtthyndl knyayntpgi enghvefdee tlrptyklri 481 gaagsshafs iserlgmpae ilakakelrs kaqdvdmeti ltklnsqskr mdeeqaeleq 541 kladvrried elrrekekvs akrqdiidss rreafdlkrn lrveaeriir elkqqskdss 601 dkekakaidq arraiqqisl pdkekprrdp vdpsqlkvgq svfinsldgl gtvteingkk 661 ltvsvrgmtv rvklqdvsap yldeikreeq aerkasasss frpirtasva telniigkty 721 qealpdvekf ldqalaagfs pvriihgkgs galrrqihef ldsqpfvkky alddveggga 781 gvtlvyf //
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Conserved Domains
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