A disintegrin and metalloproteinase with thrombospondin motifs 16 isof - Protein

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ADAMTS16 activates latent TGF-β, accentuating fibrosis and dysfunction of the pressure-overloaded heart. [Cardiovasc Res. 2020]
ADAMTS16 activates latent TGF-β, accentuating fibrosis and dysfunction of the pressure-overloaded heart.
Yao Y, Hu C, Song Q, Li Y, Da X, Yu Y, Li H, Clark IM, Chen Q, Wang QK. Cardiovasc Res. 2020 Apr 1; 116(5):956-969.
Extracellular Matrix Disorganization Caused by ADAMTS16 Deficiency Leads to Bicuspid Aortic Valve With Raphe Formation. [Circulation. 2024]
Extracellular Matrix Disorganization Caused by ADAMTS16 Deficiency Leads to Bicuspid Aortic Valve With Raphe Formation.
Lin Y, Yang Q, Lin X, Liu X, Qian Y, Xu D, Cao N, Han X, Zhu Y, Hu W, et al. Circulation. 2024 Feb 20; 149(8):605-626. Epub 2023 Nov 29.
A Selective Extracellular Matrix Proteomics Approach Identifies Fibronectin Proteolysis by A Disintegrin-like and Metalloprotease Domain with Thrombospondin Type 1 Motifs (ADAMTS16) and Its Impact on Spheroid Morphogenesis. [Mol Cell Proteomics. 2018]
A Selective Extracellular Matrix Proteomics Approach Identifies Fibronectin Proteolysis by A Disintegrin-like and Metalloprotease Domain with Thrombospondin Type 1 Motifs (ADAMTS16) and Its Impact on Spheroid Morphogenesis.
Schnellmann R, Sack R, Hess D, Annis DS, Mosher DF, Apte SS, Chiquet-Ehrismann R. Mol Cell Proteomics. 2018 Jul; 17(7):1410-1425. Epub 2018 Apr 18.

RefSeq mRNA
See reference mRNA sequence for the Adamts16 gene (XM_006517268.5).
RefSeq protein isoforms
See 12 reference sequence protein isoforms for the Adamts16 gene.

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