Q8IYL2 is a candidate gene for the familial epilepsy syndrome of Partial Epilepsy with Pericentral Spikes (PEPS).
Leschziner GD, Coffey AJ, Andrew T, Gregorio SP, Dias-Neto E, Calafato M, Bentley DR, Kinton L, Sander JW, Johnson MR. Epilepsy Res. 2011 Sep; 96(1-2):109-15. Epub 2011 Jun 11.