3-hydroxy-3-methylglutaryl-Coenzyme A reductase isoform X3 [Homo sapie - Protein

Run BLAST
Find regions of similarity between this sequence and other sequences using BLAST.
Identify Conserved Domains
View conserved domains detected in this protein sequence using CD-search.
Show in Genome Data Viewer
Opens the Genome Data Viewer, NCBI's genome browser, at the genomic location at which this sequence is annotated. View this sequence in the context of other features annotated at the same location and browse to other genome regions.

Peroxisomal Localization of a Truncated HMG-CoA Reductase under Low Cholesterol Conditions. [Biomolecules. 2024]
Peroxisomal Localization of a Truncated HMG-CoA Reductase under Low Cholesterol Conditions.
Wang J, Kunze M, Villoria-González A, Weinhofer I, Berger J. Biomolecules. 2024 Feb 19; 14(2). Epub 2024 Feb 19.
Bi-allelic variants in HMGCR cause an autosomal-recessive progressive limb-girdle muscular dystrophy. [Am J Hum Genet. 2023]
Bi-allelic variants in HMGCR cause an autosomal-recessive progressive limb-girdle muscular dystrophy.
Morales-Rosado JA, Schwab TL, Macklin-Mantia SK, Foley AR, Pinto E Vairo F, Pehlivan D, Donkervoort S, Rosenfeld JA, Boyum GE, Hu Y, et al. Am J Hum Genet. 2023 Jun 1; 110(6):989-997. Epub 2023 May 10.
Novel polymorphism of the HMGCR gene related to the risk of diabetes in premature triple-vessel disease patients. [J Gene Med. 2022]
Novel polymorphism of the HMGCR gene related to the risk of diabetes in premature triple-vessel disease patients.
Zhao X, Tang X, Xu J, Liu R, Huang K, Li J, Li Y, Jiang L, Xu L, Zhang Y, et al. J Gene Med. 2022 Sep; 24(9):e3445. Epub 2022 Sep 4.

RefSeq genomic sequence
See the genomic reference sequence for the HMGCR gene (NG_011449.1).
RefSeq mRNA
See reference mRNA sequence for the HMGCR gene (XM_011543359.2).
RefSeq protein isoforms
See 9 reference sequence protein isoforms for the HMGCR gene.

BioProject
Proteins related to BioProjects
Nucleotide
Nucleotide sequence from coding region
Taxonomy
Taxonomy sequences associated with protein record
BioSystems
BioSystems
CDD Search Results
Display conserved domains within a protein
Conserved Domains (Concise)
Link to a concise list of conserved domains in a protein
Conserved Domains (Full)
Link to conserved domains within a protein
Domain Relatives
Display proteins with similar conserved domain architecture
Encoding mRNA
Link from protein to encoding mRNA
Gene
Link to related Genes
Genome
Genome record encoding protein sequence
Identical Structures
3D structures for identical protein sequences
PubMed (RefSeq)
Link to RefSeq PubMed articles
PubMed (Weighted)
Links to pubmed
SNP
Related SNPs

Your browsing activity is empty.

Activity recording is turned off.

Protein