alkaline ceramidase 3 isoform X3 [Homo sapiens]

Run BLAST
Find regions of similarity between this sequence and other sequences using BLAST.
Identify Conserved Domains
View conserved domains detected in this protein sequence using CD-search.
Show in Genome Data Viewer
Opens the Genome Data Viewer, NCBI's genome browser, at the genomic location at which this sequence is annotated. View this sequence in the context of other features annotated at the same location and browse to other genome regions.

Alkaline ceramidase catalyzes the hydrolysis of ceramides via a catalytic mechanism shared by Zn2+-dependent amidases. [PLoS One. 2022]
Alkaline ceramidase catalyzes the hydrolysis of ceramides via a catalytic mechanism shared by Zn2+-dependent amidases.
Yi JK, Xu R, Obeid LM, Hannun YA, Airola MV, Mao C. PLoS One. 2022; 17(9):e0271540. Epub 2022 Sep 1.
ACER3-related leukoencephalopathy: expanding the clinical and imaging findings spectrum due to novel variants. [Hum Genomics. 2021]
ACER3-related leukoencephalopathy: expanding the clinical and imaging findings spectrum due to novel variants.
Dehnavi AZ, Heidari E, Rasulinezhad M, Heidari M, Ashrafi MR, Hosseini MM, Sadeghzadeh F, Fallah MS, Rostampour N, Bahraini A, et al. Hum Genomics. 2021 Jul 19; 15(1):45. Epub 2021 Jul 19.
ACER3 supports development of acute myeloid leukemia. [Biochem Biophys Res Commun. 2016]
ACER3 supports development of acute myeloid leukemia.
Chen C, Yin Y, Li C, Chen J, Xie J, Lu Z, Li M, Wang Y, Zhang CC. Biochem Biophys Res Commun. 2016 Sep 9; 478(1):33-38. Epub 2016 Jul 25.

RefSeq mRNA
See reference mRNA sequence for the ACER3 gene (XM_017017987.2).
RefSeq protein isoforms
See 12 reference sequence protein isoforms for the ACER3 gene.

BioProject
Proteins related to BioProjects
Nucleotide
Nucleotide sequence from coding region
Taxonomy
Taxonomy sequences associated with protein record
BioSystems
BioSystems
CDD Search Results
Display conserved domains within a protein
Conserved Domains (Concise)
Link to a concise list of conserved domains in a protein
Conserved Domains (Full)
Link to conserved domains within a protein
Domain Relatives
Display proteins with similar conserved domain architecture
Encoding mRNA
Link from protein to encoding mRNA
Gene
Link to related Genes
Genome
Genome record encoding protein sequence
Identical Structures
3D structures for identical protein sequences
PubMed (RefSeq)
Link to RefSeq PubMed articles
PubMed (Weighted)
Links to pubmed
SNP
Related SNPs

Your browsing activity is empty.

Activity recording is turned off.

Protein