THO complex subunit 1 isoform X4 [Homo sapiens]

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Knockdown of THOC1 reduces the proliferation of hepatocellular carcinoma and increases the sensitivity to cisplatin. [J Exp Clin Cancer Res. 2020]
Knockdown of THOC1 reduces the proliferation of hepatocellular carcinoma and increases the sensitivity to cisplatin.
Cai S, Bai Y, Wang H, Zhao Z, Ding X, Zhang H, Zhang X, Liu Y, Jia Y, Li Y, et al. J Exp Clin Cancer Res. 2020 Jul 15; 39(1):135. Epub 2020 Jul 15.
Elevated expression of Thoc1 is associated with aggressive phenotype and poor prognosis in colorectal cancer. [Biochem Biophys Res Commun. 2015]
Elevated expression of Thoc1 is associated with aggressive phenotype and poor prognosis in colorectal cancer.
Liu C, Yue B, Yuan C, Zhao S, Fang C, Yu Y, Yan D. Biochem Biophys Res Commun. 2015 Dec 4-11; 468(1-2):53-8. Epub 2015 Nov 3.
Thoc1 inhibits cell growth via induction of cell cycle arrest and apoptosis in lung cancer cells. [Mol Med Rep. 2014]
Thoc1 inhibits cell growth via induction of cell cycle arrest and apoptosis in lung cancer cells.
Wan J, Zou S, Hu M, Zhu R, Xu J, Jiao Y, Fan S. Mol Med Rep. 2014 Jun; 9(6):2321-7. Epub 2014 Mar 28.

RefSeq mRNA
See reference mRNA sequence for the THOC1 gene (XM_017026104.2).
RefSeq protein isoforms
See 9 reference sequence protein isoforms for the THOC1 gene.

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Protein