LOCUS NP_012790 430 aa linear PLN 17-DEC-2024
DEFINITION putative tetrahydrofolate synthase [Saccharomyces cerevisiae
S288C].
ACCESSION NP_012790
VERSION NP_012790.1
DBLINK BioProject: PRJNA128
DBSOURCE REFSEQ: accession NM_001179698.1
KEYWORDS RefSeq.
SOURCE Saccharomyces cerevisiae S288C
ORGANISM Saccharomyces cerevisiae S288C
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
Saccharomycetes; Saccharomycetales; Saccharomycetaceae;
Saccharomyces.
REFERENCE 1 (residues 1 to 430)
AUTHORS Engel,S.R., Wong,E.D., Nash,R.S., Aleksander,S., Alexander,M.,
Douglass,E., Karra,K., Miyasato,S.R., Simison,M., Skrzypek,M.S.,
Weng,S. and Cherry,J.M.
TITLE New data and collaborations at the Saccharomyces Genome Database:
updated reference genome, alleles, and the Alliance of Genome
Resources
JOURNAL Genetics 220 (4) (2022)
PUBMED 34897464
REFERENCE 2 (residues 1 to 430)
AUTHORS Goffeau,A., Barrell,B.G., Bussey,H., Davis,R.W., Dujon,B.,
Feldmann,H., Galibert,F., Hoheisel,J.D., Jacq,C., Johnston,M.,
Louis,E.J., Mewes,H.W., Murakami,Y., Philippsen,P., Tettelin,H. and
Oliver,S.G.
TITLE Life with 6000 genes
JOURNAL Science 274 (5287), 546 (1996)
PUBMED 8849441
REFERENCE 3 (residues 1 to 430)
AUTHORS Dujon,B., Alexandraki,D., Andre,B., Ansorge,W., Baladron,V.,
Ballesta,J.P., Banrevi,A., Bolle,P.A., Bolotin-Fukuhara,M.,
Bossier,P. et al.
TITLE Complete DNA sequence of yeast chromosome XI
JOURNAL Nature 369 (6479), 371-378 (1994)
PUBMED 8196765
REFERENCE 4 (residues 1 to 430)
CONSRTM NCBI Genome Project
TITLE Direct Submission
JOURNAL Submitted (17-DEC-2024) National Center for Biotechnology
Information, NIH, Bethesda, MD 20894, USA
REFERENCE 5 (residues 1 to 430)
CONSRTM Saccharomyces Genome Database
TITLE Direct Submission
JOURNAL Submitted (04-MAY-2012) Department of Genetics, Stanford
University, Stanford, CA 94305-5120, USA
REMARK Protein update by submitter
REFERENCE 6 (residues 1 to 430)
CONSRTM Saccharomyces Genome Database
TITLE Direct Submission
JOURNAL Submitted (31-MAR-2011) Department of Genetics, Stanford
University, Stanford, CA 94305-5120, USA
REMARK Sequence update by submitter
REFERENCE 7 (residues 1 to 430)
CONSRTM Saccharomyces Genome Database
TITLE Direct Submission
JOURNAL Submitted (14-DEC-2009) Department of Genetics, Stanford
University, Stanford, CA 94305-5120, USA
COMMENT REVIEWED REFSEQ: This record has been curated by SGD. The reference
sequence is identical to DAA09030.
##Genome-Annotation-Data-START##
Annotation Provider :: SGD
Annotation Status :: Full Annotation
Annotation Version :: R64-4-1
URL :: http://www.yeastgenome.org/
##Genome-Annotation-Data-END##
Method: conceptual translation.
FEATURES Location/Qualifiers
source 1..430
/organism="Saccharomyces cerevisiae S288C"
/strain="S288C"
/db_xref="taxon:559292"
/chromosome="XI"
Protein 1..430
/product="putative tetrahydrofolate synthase"
/EC_number="6.3.2.17"
/calculated_mol_wt=48012
Region 10..424
/region_name="PLN02881"
/note="tetrahydrofolylpolyglutamate synthase; cl47075"
/db_xref="CDD:481415"
CDS 1..430
/gene="RMA1"
/locus_tag="YKL132C"
/coded_by="NM_001179698.1:1..1293"
/experiment="EXISTENCE:direct assay:GO:0005739
mitochondrion [PMID:16823961|PMID:14576278]"
/note="Putative dihydrofolate synthetase; similar to E.
coli folylpolyglutamate synthetase/dihydrofolate
synthetase; the authentic, non-tagged protein is detected
in highly purified mitochondria in high-throughput
studies; RMA1 has a paralog, FOL3, that arose from the
whole genome duplication"
/db_xref="GeneID:853727"
/db_xref="SGD:S000001615"
ORIGIN
1 mddisgrqtl prinrllehv gnpqdslsil hiagtngket vskfltsilq hpgqqrqrvl
61 igryttssll nakeedisin neaislieys riekeliead sslklqcnnl elltsvalvy
121 fakkncqwci ietglagkqd pgsiiagqsr vccaitnvgi sdeaflckfl sqitesstnk
181 aiflldgsnd efvrntitkr chdvgcplei tdpslrdynv htdtwgtlev rlpyseeeyq
241 ifnlrvaiav ldflskekkv ciskdqlsqg lisvdwprsl hrldycyest sgkkiallld
301 nannakaarn lachlrttyg dtpltfviai ttgkkvspll dplirpqdyv ivtrfgsvvg
361 mpwiqslepv nllafiknry trnvnmqpdl qsvwtflets glktivpviv cgslyickel
421 lrlhnchlpv
//