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putative tetrahydrofolate synthase [Saccharomyces cerevisiae S288C]

NCBI Reference Sequence: NP_012790.1

Identical Proteins FASTA Graphics 

LOCUS       NP_012790                430 aa            linear   PLN 17-DEC-2024
DEFINITION  putative tetrahydrofolate synthase [Saccharomyces cerevisiae
            S288C].
ACCESSION   NP_012790
VERSION     NP_012790.1
DBLINK      BioProject: PRJNA128
DBSOURCE    REFSEQ: accession NM_001179698.1
KEYWORDS    RefSeq.
SOURCE      Saccharomyces cerevisiae S288C
  ORGANISM  Saccharomyces cerevisiae S288C
            Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
            Saccharomycetes; Saccharomycetales; Saccharomycetaceae;
            Saccharomyces.
REFERENCE   1  (residues 1 to 430)
  AUTHORS   Engel,S.R., Wong,E.D., Nash,R.S., Aleksander,S., Alexander,M.,
            Douglass,E., Karra,K., Miyasato,S.R., Simison,M., Skrzypek,M.S.,
            Weng,S. and Cherry,J.M.
  TITLE     New data and collaborations at the Saccharomyces Genome Database:
            updated reference genome, alleles, and the Alliance of Genome
            Resources
  JOURNAL   Genetics 220 (4) (2022)
   PUBMED   34897464
REFERENCE   2  (residues 1 to 430)
  AUTHORS   Goffeau,A., Barrell,B.G., Bussey,H., Davis,R.W., Dujon,B.,
            Feldmann,H., Galibert,F., Hoheisel,J.D., Jacq,C., Johnston,M.,
            Louis,E.J., Mewes,H.W., Murakami,Y., Philippsen,P., Tettelin,H. and
            Oliver,S.G.
  TITLE     Life with 6000 genes
  JOURNAL   Science 274 (5287), 546 (1996)
   PUBMED   8849441
REFERENCE   3  (residues 1 to 430)
  AUTHORS   Dujon,B., Alexandraki,D., Andre,B., Ansorge,W., Baladron,V.,
            Ballesta,J.P., Banrevi,A., Bolle,P.A., Bolotin-Fukuhara,M.,
            Bossier,P. et al.
  TITLE     Complete DNA sequence of yeast chromosome XI
  JOURNAL   Nature 369 (6479), 371-378 (1994)
   PUBMED   8196765
REFERENCE   4  (residues 1 to 430)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-DEC-2024) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   5  (residues 1 to 430)
  CONSRTM   Saccharomyces Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2012) Department of Genetics, Stanford
            University, Stanford, CA 94305-5120, USA
  REMARK    Protein update by submitter
REFERENCE   6  (residues 1 to 430)
  CONSRTM   Saccharomyces Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (31-MAR-2011) Department of Genetics, Stanford
            University, Stanford, CA 94305-5120, USA
  REMARK    Sequence update by submitter
REFERENCE   7  (residues 1 to 430)
  CONSRTM   Saccharomyces Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (14-DEC-2009) Department of Genetics, Stanford
            University, Stanford, CA 94305-5120, USA
COMMENT     REVIEWED REFSEQ: This record has been curated by SGD. The reference
            sequence is identical to DAA09030.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider :: SGD
            Annotation Status   :: Full Annotation
            Annotation Version  :: R64-4-1
            URL                 :: http://www.yeastgenome.org/
            ##Genome-Annotation-Data-END##
            Method: conceptual translation.
FEATURES             Location/Qualifiers
     source          1..430
                     /organism="Saccharomyces cerevisiae S288C"
                     /strain="S288C"
                     /db_xref="taxon:559292"
                     /chromosome="XI"
     Protein         1..430
                     /product="putative tetrahydrofolate synthase"
                     /EC_number="6.3.2.17"
                     /calculated_mol_wt=48012
     Region          10..424
                     /region_name="PLN02881"
                     /note="tetrahydrofolylpolyglutamate synthase; cl47075"
                     /db_xref="CDD:481415"
     CDS             1..430
                     /gene="RMA1"
                     /locus_tag="YKL132C"
                     /coded_by="NM_001179698.1:1..1293"
                     /experiment="EXISTENCE:direct assay:GO:0005739
                     mitochondrion [PMID:16823961|PMID:14576278]"
                     /note="Putative dihydrofolate synthetase; similar to E.
                     coli folylpolyglutamate synthetase/dihydrofolate
                     synthetase; the authentic, non-tagged protein is detected
                     in highly purified mitochondria in high-throughput
                     studies; RMA1 has a paralog, FOL3, that arose from the
                     whole genome duplication"
                     /db_xref="GeneID:853727"
                     /db_xref="SGD:S000001615"
ORIGIN      
        1 mddisgrqtl prinrllehv gnpqdslsil hiagtngket vskfltsilq hpgqqrqrvl
       61 igryttssll nakeedisin neaislieys riekeliead sslklqcnnl elltsvalvy
      121 fakkncqwci ietglagkqd pgsiiagqsr vccaitnvgi sdeaflckfl sqitesstnk
      181 aiflldgsnd efvrntitkr chdvgcplei tdpslrdynv htdtwgtlev rlpyseeeyq
      241 ifnlrvaiav ldflskekkv ciskdqlsqg lisvdwprsl hrldycyest sgkkiallld
      301 nannakaarn lachlrttyg dtpltfviai ttgkkvspll dplirpqdyv ivtrfgsvvg
      361 mpwiqslepv nllafiknry trnvnmqpdl qsvwtflets glktivpviv cgslyickel
      421 lrlhnchlpv
//
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