RecName: Full=1-phosphatidylinositol 3-phosphate 5-kinase; Short=Phosp - Protein

Run BLAST
Find regions of similarity between this sequence and other sequences using BLAST.
Identify Conserved Domains
View conserved domains detected in this protein sequence using CD-search.
Highlight Sequence Features
Opens the Highlight Feature Bar and highlights feature annotations from the FEATURES table of the record. The Highlight Feature Bar can be used to navigate to and highlight other features and provides links to display the highlighted region separately. Links in the FEATURES table will also highlight the corresponding region of the sequence. More...
Find in this Sequence
Finds sub-sequences or patterns in the sequence and highlights the matching regions. The tool works with standard single letter nucleotide or protein codes including ambiguities and can match Prosite patterns in protein sequences. More...

Coxiella burnetii effector CvpE maintains biogenesis of Coxiella-containing vacuoles by suppressing lysosome tubulation through binding PI(3)P and perturbing PIKfyve activity on lysosomes. [Virulence. 2024]
Coxiella burnetii effector CvpE maintains biogenesis of Coxiella-containing vacuoles by suppressing lysosome tubulation through binding PI(3)P and perturbing PIKfyve activity on lysosomes.
Zhao M, Zhang S, Wan W, Zhou C, Li N, Cheng R, Yu Y, Ouyang X, Zhou D, Jiao J, et al. Virulence. 2024 Dec; 15(1):2350893. Epub 2024 May 9.
Stress-induced microautophagy is coordinated with lysosome biogenesis and regulated by PIKfyve. [Mol Biol Cell. 2024]
Stress-induced microautophagy is coordinated with lysosome biogenesis and regulated by PIKfyve.
Klein AD, Petruzzi KL, Lee C, Overholtzer M. Mol Biol Cell. 2024 May 1; 35(5):ar70. Epub 2024 Mar 27.
Autophagy Inhibition by Targeting PIKfyve Potentiates Response to Immune Checkpoint Blockade in Prostate Cancer. [Nat Cancer. 2021]
Autophagy Inhibition by Targeting PIKfyve Potentiates Response to Immune Checkpoint Blockade in Prostate Cancer.
Qiao Y, Choi JE, Tien JC, Simko SA, Rajendiran T, Vo JN, Delekta AD, Wang L, Xiao L, Hodge NB, et al. Nat Cancer. 2021 Sep; 2:978-993. Epub 2021 Aug 2.

RefSeq genomic sequence
See the genomic reference sequence for the PIKFYVE gene (NG_021188.2).
RefSeq protein isoforms
See 77 reference sequence protein isoforms for the PIKFYVE gene.

PubMed
PubMed articles cited by protein sequence record
Taxonomy
Taxonomy sequences associated with protein record
BioAssay by Target (Summary)
BioAssay by Target (Summary)
BioSystems
BioSystems
CDD Search Results
Display conserved domains within a protein
Conserved Domains (Concise)
Link to a concise list of conserved domains in a protein
Conserved Domains (Full)
Link to conserved domains within a protein
Domain Relatives
Display proteins with similar conserved domain architecture
Full text in PMC
Free full text articles in PMC
Gene
Link to related Genes
OMIM
OMIM records associated with protein sequence
Protein (RefSeq)
Protein gi (UniProtKB) to protein gi (refseq)
PubMed (Weighted)
Links to pubmed
Related Structures (List)
List of related structures

Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
Reactome [Reactome]
Reactome
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome
reagent reviews [ExactAntigen/Labome]
reagent reviews
ExactAntigen/Labome

RecName: Full=1-phosphatidylinositol 3-phosphate 5-kinase; Short=Phosphatidylino...
RecName: Full=1-phosphatidylinositol 3-phosphate 5-kinase; Short=Phosphatidylinositol 3-phosphate 5-kinase; AltName: Full=FYVE finger-containing phosphoinositide kinase; AltName: Full=PIKfyve; AltName: Full=Phosphatidylinositol 3-phosphate 5-kinase type III; Short=PIPkin-III; Short=Type III PIP kinase; AltName: Full=Serine-protein kinase PIKFYVE
gi|300669693|sp|Q9Y2I7.3|FYV1_HUMAN

Protein

Your browsing activity is empty.

Activity recording is turned off.

Protein