RecName: Full=Mitogen-activated protein kinase kinase kinase kinase 2; - Protein

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MAP4K2 connects the Hippo pathway to autophagy in response to energy stress. [Autophagy. 2024]
MAP4K2 connects the Hippo pathway to autophagy in response to energy stress.
Seo G, Mckinley J, Wang W. Autophagy. 2024 Mar; 20(3):704-706. Epub 2023 Nov 15.
Pathophysiological significance and therapeutic targeting of germinal center kinase in diffuse large B-cell lymphoma. [Blood. 2016]
Pathophysiological significance and therapeutic targeting of germinal center kinase in diffuse large B-cell lymphoma.
Matthews JM, Bhatt S, Patricelli MP, Nomanbhoy TK, Jiang X, Natkunam Y, Gentles AJ, Martinez E, Zhu D, Chapman JR, et al. Blood. 2016 Jul 14; 128(2):239-48. Epub 2016 May 5.
Differential expression of a novel protein kinase in human B lymphocytes. Preferential localization in the germinal center. [J Biol Chem. 1994]
Differential expression of a novel protein kinase in human B lymphocytes. Preferential localization in the germinal center.
Katz P, Whalen G, Kehrl JH. J Biol Chem. 1994 Jun 17; 269(24):16802-9.

RefSeq genomic sequence
See the genomic reference sequence for the MAP4K2 gene (NG_033040.2).
RefSeq protein isoforms
See 2 reference sequence protein isoforms for the MAP4K2 gene.

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Q12851 [Domain Mapping of Disease Mut...]
Q12851
Domain Mapping of Disease Mutations
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
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Reactome
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reagents
ExactAntigen/Labome

RecName: Full=Mitogen-activated protein kinase kinase kinase kinase 2; AltName: ...
RecName: Full=Mitogen-activated protein kinase kinase kinase kinase 2; AltName: Full=B lymphocyte serine/threonine-protein kinase; AltName: Full=Germinal center kinase; Short=GC kinase; AltName: Full=MAPK/ERK kinase kinase kinase 2; Short=MEK kinase kinase 2; Short=MEKKK 2; AltName: Full=Rab8-interacting protein
gi|215274019|sp|Q12851.2|M4K2_HUMAN

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