Protein Family Models for Gene (Select 1188005) - Protein Family Models

Select item 3903941.

new record, indexing in progress

Family Accession:

Select item 3501262.

new record, indexing in progress

Family Accession:

Select item 2511523.

4-hydroxy-3-methylbut-2-enyl diphosphate reductase

4-hydroxy-3-methylbut-2-enyl diphosphate reductase converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) in the non-mevalonate pathway for isoprenoid synthesis

Date:: 2022-08-29

Family Accession:: 10011613
Method:: Sparcle

Select item 1777414.

4-hydroxy-3-methylbut-2-enyl diphosphate reductase

Date:: 2020-10-26

Family Accession:: NF002190.0
Method:: HMM

Select item 1777405.

4-hydroxy-3-methylbut-2-enyl diphosphate reductase

Gene:: ispH

GO Terms:

Biological Process:: isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway (GO:0019288)

Molecular Function:: metal ion binding (GO:0046872)

Biological Process:: dimethylallyl diphosphate biosynthetic process (GO:0050992)

Molecular Function:: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase activity (GO:0051745)

Date:: 2021-07-28

Family Accession:: NF002188.0
Method:: HMM

Select item 168476.

4-hydroxy-3-methylbut-2-enyl diphosphate reductase

The IspH protein (previously designated LytB) has now been recognized as the last enzyme in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Escherichia coli LytB protein had been found to regulate the activity of RelA (guanosine 3',5'-bispyrophosphate synthetase I), which in turn controls the level of a regulatory metabolite. It is involved in penicillin tolerance and the stringent response.

Gene:: ispH

GO Terms:

Biological Process:: isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway (GO:0019288)

Molecular Function:: metal ion binding (GO:0046872)

Biological Process:: dimethylallyl diphosphate biosynthetic process (GO:0050992)

Molecular Function:: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase activity (GO:0051745)

Date:: 2024-06-21

Family Accession:: TIGR00216.1
Method:: HMM

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