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O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase
This HMM describes a distinct clade of the Cys/Met metabolism pyridoxal phosphate-dependent enzyme superfamily. Members include examples of OAH/OAS sulfhydrylase, an enzyme with activity both as O-acetylhomoserine (OAH) sulfhydrylase (EC 2.5.1.49) and O-acetylserine (OAS) sulphydrylase (EC 2.5.1.47). An alternate name for OAH sulfhydrylase is homocysteine synthase. This HMM is designated subfamily because it may or may not have both activities.
O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase is a PLP-dependent enzyme that catalyzes the conversion of O-acetyl-L-homoserine (OAH) into homocysteine in the methionine biosynthesis pathway and/or catalyzes the conversion of O-acetylserine (OAS) into cysteine in the last step of the cysteine biosynthesis pathway
bifunctional o-acetylhomoserine/o-acetylserine sulfhydrylase
Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
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