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D-aminoacyl-tRNA deacylase
D-aminoacyl-tRNA deacylase hydrolyzes D-aminoacyl-tRNA into D-amino acids and free tRNA which may be a defense mechanism against harmful effects of incorporating D-amino acids
This homodimeric enzyme, D-aminoacyl-tRNA deacylase, appears able to cleave any D-amino acid (and glycine, which does not have distinct D/L forms) from mis-charged tRNA molecules. The old name D-tyrosyl-tRNA(Tyr) deacylase reflects characterization with respect to D-Tyr on tRNA(Tyr) as established in the literature, but substrate specificity seems much broader.
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