Transcriptional repressors that sense toxic heavy metals such as arsenic or cadmium, and are released from DNA so that resistance factors will be expressed, include ArsR, SmtB, ZiaR, CadC, CadX, KmtR, etc. However, some members of this family, including the sporulation delaying system autorepressor SdpR and its family (see NF033789), may lack metal-binding cites and instead regulate other cellular processes.
GO Terms:- Molecular Function:
- DNA-binding transcription factor activity (GO:0003700)
- Biological Process:
- regulation of DNA-templated transcription (GO:0006355)
- Date:
- 2021-12-28