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Items: 5

1.
new record, indexing in progress
Family Accession:
2.
new record, indexing in progress
Family Accession:
3.
new record, indexing in progress
Family Accession:
4.

23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN

23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN is a dual-specificity RNA methyltransferase that specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs

Date:
2024-08-01
Family Accession:
11435290
Method:
Sparcle
5.

23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN

Members of this family are RlmN, a 23S rRNA m2A2503 methyltransferase in the radical SAM enzyme family. Closely related is Cfr, a Staphylococcus sciuri plasmid-borne homolog to this family the confers transferrable resistance to chloramphenicol and florfenicol. Cfr methylates adenine(2503) of 23S RNA at position C(8), while RlmN methylates the same residue at a different site, position C(2).

Gene:
rlmN
GO Terms:
Molecular Function:
S-adenosylmethionine-dependent methyltransferase activity (GO:0008757)
Molecular Function:
rRNA (adenine) methyltransferase activity (GO:0016433)
Biological Process:
tRNA methylation (GO:0030488)
Biological Process:
rRNA base methylation (GO:0070475)
Date:
2024-06-21
Family Accession:
TIGR00048.1
Method:
HMM
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