Elongation factor P (EF-P) alleviates stalling of protein translation at polyproline sites. EF-P (and its archaeal and eukaryotic homologs) are post-translationally modified, on a critical lysine or arginine residue, in different ways in different lineages. Residues are modified with beta-lysine, rhamnose, 5-aminopentanol, or hypusine. The trusted cutoff of this model is set high enough to exclude members of TIGR02178, the EFP-like protein YeiP found in certain Gammaproteobacteria.
- Gene:
- efp
GO Terms:- Molecular Function:
- translation elongation factor activity (GO:0003746)
- Cellular Component:
- cytoplasm (GO:0005737)
- Biological Process:
- translational elongation (GO:0006414)
- Date:
- 2024-08-05