Protein Family Models for Gene (Select 61610824) - Protein Family Models

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Select item 2160569.

double-strand break repair helicase AddA

double-strand break repair helicase AddA, with RexB, forms a heterodimer that acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease, which recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination

Date:: 2020-10-22

Family Accession:: 11494989
Method:: Sparcle

Select item 5044610.

double-strand break repair helicase AddA

AddAB, also called RexAB, substitutes for RecBCD in several bacterial lineages. These DNA recombination proteins act before synapse and are particularly important for DNA repair of double-stranded breaks by homologous recombination. The term AddAB is used broadly, with AddA homologous between the alphaproteobacteria (as modeled here) and the Firmicutes, while the partner AddB proteins show no strong homology across the two groups of species.

Gene:: addA

GO Terms:

Biological Process:: double-strand break repair via homologous recombination (GO:0000724)

Date:: 2021-04-27

Family Accession:: TIGR02784.1
Method:: HMM

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