Protein Family Models for Gene (Select 61871440) - Protein Family Models

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Items: 4

Select item 3883481.

new record, indexing in progress

Family Accession:

Select item 3468332.

new record, indexing in progress

Family Accession:

Select item 2536823.

ribonuclease T

ribonuclease T is a 3'-5' exonuclease implicated in the 3' maturation of small stable RNAs and 23srRNA, and in the end turnover of tRNA

Date:: 2022-11-14

Family Accession:: 10150094
Method:: Sparcle

Select item 1419464.

ribonuclease T

This HMM describes ribonuclease T, an enzyme found so far only in gamma-subdivision Proteobacteria such as Escherichia coli and Xylella fastidiosa. Ribonuclease T is homologous to the DNA polymerase III alpha chain. It can liberate AMP from the common C-C-A terminus of uncharged tRNA. It appears also to be involved in RNA maturation. It also acts as a 3' to 5' single-strand DNA-specific exonuclease; it is distinctive for its ability to remove residues near a double-stranded stem. Ribonuclease T is a high copy suppressor in E. coli of a uv-repair defect caused by deletion of three other single-stranded DNA exonucleases.