Protein Family Models for Gene (Select 64183372) - Protein Family Models

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Links from Gene

Items: 6

Select item 3908681.

new record, indexing in progress

Family Accession:

Select item 3487552.

new record, indexing in progress

Family Accession:

Select item 2515803.

ammonia-dependent NAD(+) synthetase

ammonia-dependent NAD(+) synthetase converts deamido-NAD+ to NAD+, utilizing NH(3) as the nitrogen source

Date:: 2024-06-26

Family Accession:: 10011511
Method:: Sparcle

Select item 1926004.

ammonia-dependent NAD(+) synthetase

Gene:: nadE

Date:: 2018-09-27

Family Accession:: NBR006743
Method:: BlastRule

Select item 236675.

ammonia-dependent NAD(+) synthetase

Catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia as the amide donor and ATP forms homodimers

Gene:: nadE

GO Terms:

Molecular Function:: NAD+ synthase (glutamine-hydrolyzing) activity (GO:0003952)

Molecular Function:: glutaminase activity (GO:0004359)

Molecular Function:: NAD+ synthase activity (GO:0008795)

Biological Process:: NAD biosynthetic process (GO:0009435)

Date:: 2021-07-28

Family Accession:: NF001979.0
Method:: HMM

Select item 203026.

NAD(+) synthase

NAD+ synthetase is a nearly ubiquitous enzyme for the final step in the biosynthesis of the essensial cofactor NAD. The member of this family from Bacillus subtilis is a strictly NH(3)-dependent NAD(+) synthetase of 272 amino acids. Proteins consisting only of the domain modeled here may be named as NH3-dependent NAD+ synthetase. Amidotransferase activity may reside in a separate protein, or not be present. Some other members of the family, such as from Mycobacterium tuberculosis, are considerably longer, contain an apparent amidotransferase domain, and show glutamine-dependent as well as NH(3)-dependent activity.