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carboxymuconolactone decarboxylase family protein
carboxymuconolactone decarboxylase (CMD) family protein; similar to Anaeromyxobacter sp. alkyl hydroperoxide reductase AhpD, which is required for the reduction of the AhpC active site cysteine residues to regenerate its enzyme activity, and to Saccharomyces cerevisiae peroxisomal protein 2 (Pxp2) which is probably involved in peroxisome formation or maintenance as well as in amino acid metabolism
alkylhydroperoxidase AhpD family core domain
This HMM represents a 51-residue core region of homology among a family of mostly uncharacterized proteins of 110 to 227 amino acids. Most members of this family contain the motif EXXXXXX[SA]XXXXXC[VIL]XCXXXH. Members of the family include the alkylhydroperoxidase AhpD of Mycobacterium tuberculosis, a macrophage infectivity potentiator peptide of Legionella pneumophila, and an uncharacterized peptide in the tetrachloroethene reductive dehalogenase operon of Dehalospirillum multivorans. We suggest that many peptides containing this domain may have alkylhydroperoxidase or related antioxidant activity.
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