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glyceraldehyde-3-phosphate dehydrogenase
type I glyceraldehyde-3-phosphate dehydrogenase
This HMM represents glyceraldehyde-3-phosphate dehydrogenase (GAPDH), the enzyme responsible for the interconversion of 1,3-diphosphoglycerate and glyceraldehyde-3-phosphate, a central step in glycolysis and gluconeogenesis. Forms exist which utilize NAD (EC 1.2.1.12), NADP (EC 1.2.1.13) or either (1.2.1.59). In some species, distinct NAD- and NADP- utilizing forms exist, typically being responsible for reactions in the anabolic and catabolic directions respectively [1].
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