This HMM describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone.
- Gene:
- nuoN
GO Terms:- Molecular Function:
- NADH dehydrogenase (ubiquinone) activity (GO:0008137)
- Biological Process:
- ATP synthesis coupled electron transport (GO:0042773)
- Date:
- 2024-05-30