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Items: 5

1.
new record, indexing in progress
Family Accession:
2.
new record, indexing in progress
Family Accession:
3.

holo-ACP synthase

holo-[acyl-carrier-protein] synthase transfers the 4'-phosphopantetheine moiety from coenzyme A to a serine of acyl-carrier-protein (ACP)

Date:
2023-03-01
Family Accession:
10011191
Method:
Sparcle
4.

phosphopantetheine--protein transferase domain

This HMM models a domain active in transferring the phophopantetheine prosthetic group to its attachment site on enzymes and carrier proteins. Many members of this family are small proteins that act on the acyl carrier protein involved in fatty acid biosynthesis. Some members are domains of larger proteins involved specialized pathways for the synthesis of unusual molecules including polyketides, atypical fatty acids, and antibiotics.

GO Terms:
Molecular Function:
magnesium ion binding (GO:0000287)
Biological Process:
fatty acid biosynthetic process (GO:0006633)
Molecular Function:
holo-[acyl-carrier-protein] synthase activity (GO:0008897)
Date:
2024-05-30
Family Accession:
TIGR00556.1
Method:
HMM
5.

holo-ACP synthase

Formerly dpj. This enzyme adds the prosthetic group, phosphopantethiene, to the acyl carrier protein (ACP) apo-enzyme to generate the holo-enzyme. Related phosphopantethiene--protein transferases also exist. There is an orthologous domain in eukaryotic proteins.

Gene:
acpS
GO Terms:
Biological Process:
lipid biosynthetic process (GO:0008610)
Molecular Function:
holo-[acyl-carrier-protein] synthase activity (GO:0008897)
Date:
2021-04-27
Family Accession:
TIGR00516.1
Method:
HMM
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