Protein Family Models for Gene (Select 8153904) - Protein Family Models

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Links from Gene

Items: 7

Select item 3917801.

new record, indexing in progress

Family Accession:

Select item 3883112.

new record, indexing in progress

Family Accession:

Select item 3499683.

new record, indexing in progress

Family Accession:

Select item 3481164.

new record, indexing in progress

Family Accession:

Select item 1960595.

Spx/MgsR family RNA polymerase-binding regulatory protein

Spx/MgsR family RNA polymerase-binding regulatory protein may function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress by binding the alpha subunit of RNA polymerase, and affecting its binding of DNA

Date:: 2019-08-13

Family Accession:: 10792181
Method:: Sparcle

Select item 1786046.

transcriptional regulator Spx

Gene:: spx

Date:: 2020-10-26

Family Accession:: NF002459.0
Method:: HMM

Select item 1427617.

Spx/MgsR family RNA polymerase-binding regulatory protein

Members of this family regulate transcription by binding the alpha subunit of RNA polymerase, and affecting its binding of DNA, rather than by binding DNA directly. Characterized members of this family include Spx and MgsR from Bacillus subtili. Spx is a global regulator for response to thiol-specific oxidative stress. MgsR (modulator of the general stress response, also called YqgZ) provides a second level of regulation for more than a third of the proteins in the B. subtilis general stress regulon controlled by Sigma-B. Members are related to the arsenate reductase ArsC.