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Items: 8

1.
new record, indexing in progress
Family Accession:
2.
new record, indexing in progress
Family Accession:
3.
new record, indexing in progress
Family Accession:
4.
new record, indexing in progress
Family Accession:
5.

DNA gyrase subunit A

DNA gyrase subunit A (GyrA) forms a 2:2 heterotetrameric complex with GyrB to form gyrase, a type II topoisomerase that negatively supercoils closed circular double-stranded DNA in an ATP-dependent manner to maintain chromosomes in an underwound state

Date:
2024-04-25

Family Accession:
11481075
Method:
Sparcle

6.

DNA gyrase subunit A

Negatively supercoils closed circular double-stranded DNA

Gene:
gyrA
GO Terms:
Molecular Function:
DNA binding (GO:0003677)
Molecular Function:
DNA topoisomerase activity (GO:0003916)
Molecular Function:
DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity (GO:0003918)
Molecular Function:
ATP binding (GO:0005524)
Biological Process:
DNA metabolic process (GO:0006259)
Biological Process:
DNA topological change (GO:0006265)
Date:
2021-07-21

Family Accession:
NF004043.1
Method:
HMM

7.

DNA topoisomerase (ATP-hydrolyzing)

This HMM identifies type II DNA topoisomerases such as ParC (DNA topoisomerase IV subunit A) and GyrA (DNA gyrase subunit A).

GO Terms:
Molecular Function:
DNA binding (GO:0003677)
Molecular Function:
DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity (GO:0003918)
Molecular Function:
ATP binding (GO:0005524)
Biological Process:
DNA topological change (GO:0006265)
Date:
2023-06-29

Family Accession:
NF004044.1
Method:
HMM

8.

DNA topoisomerase (ATP-hydrolyzing) subunit A

This model describes the common type II DNA topoisomerase (DNA gyrase). Two apparently independently arising families, one in the Proteobacteria and one in Gram-positive lineages, are both designated toposisomerase IV.

Gene:
gyrA
GO Terms:
Molecular Function:
DNA topoisomerase activity (GO:0003916)
Molecular Function:
DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity (GO:0003918)
Biological Process:
DNA topological change (GO:0006265)
Cellular Component:
DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex (GO:0009330)
Date:
2021-04-27

Family Accession:
TIGR01063.1
Method:
HMM

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