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trigger factor
trigger factor functions as a peptidylprolyl isomerase that is involved in protein export and acts as a chaperone by maintaining the newly synthesized protein in an open conformation
Trigger factor is a ribosome-associated molecular chaperone and is the first chaperone to interact with nascent polypeptide. Trigger factor can bind at the same time as the signal recognition particle (SRP), but is excluded by the SRP receptor (FtsY). The central domain of trigger factor has peptidyl-prolyl cis/trans isomerase activity. This protein is found in a single copy in virtually every bacterial genome.
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