Protein Family Models for Gene (Select 87006328) - Protein Family Models

Select item 4077371.

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Family Accession:

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Select item 29524412.

ATP-dependent zinc metalloprotease FtsH

FtsH, a hexamer-forming membrane-anchored metalloprotease, belongs to the AAA family of ATPases and uses ATP for unfolding rather than to drive proteolysis directly. Substrates include damaged or misfolded proteins, as FtsH works in membrane protein quality control, but also specific substrates targeted for degradation by various regulatory circuits. FtsH was known historically as a cell division protein, and the designation HflB was used at one time, but is not currently favored.

Gene:: ftsH

GO Terms:

Molecular Function:: metalloendopeptidase activity (GO:0004222)

Biological Process:: proteolysis (GO:0006508)

Cellular Component:: membrane (GO:0016020)

Molecular Function:: ATP hydrolysis activity (GO:0016887)

Biological Process:: cell division (GO:0051301)

Date:: 2024-05-30

Family Accession:: TIGR01241.2
Method:: HMM

Select item 21561513.

ATP-dependent zinc metalloprotease FtsH

ATP-dependent zinc metalloprotease FtsH acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins

Date:: 2021-01-11

Family Accession:: 11484915
Method:: Sparcle

Select item 14193214.

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Family Accession:

Select item 2404715.

ATP-dependent zinc metalloprotease FtsH

Gene:: ftsH

GO Terms:

Molecular Function:: ATP-dependent peptidase activity (GO:0004176)

Molecular Function:: metalloendopeptidase activity (GO:0004222)

Biological Process:: proteolysis (GO:0006508)

Date:: 2021-08-26

Family Accession:: NF008004.0
Method:: HMM

Select item 1559416.

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Protein Family Models

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