Protein Family Models for Gene (Select 88185996) - Protein Family Models

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Links from Gene

Items: 6

Select item 3905931.

new record, indexing in progress

Family Accession:

Select item 3495132.

new record, indexing in progress

Family Accession:

Select item 1798373.

exodeoxyribonuclease III

Removes the damaged DNA at cytosines and guanines by cleaving on the 3' side of the AP site by a beta-elimination reaction

Gene:: xthA

GO Terms:

Molecular Function:: DNA binding (GO:0003677)

Molecular Function:: endonuclease activity (GO:0004519)

Biological Process:: DNA repair (GO:0006281)

Molecular Function:: double-stranded DNA 3'-5' DNA exonuclease activity (GO:0008311)

Date:: 2023-05-09

Family Accession:: NF008733.0
Method:: HMM

Select item 544224.

exodeoxyribonuclease III

exodeoxyribonuclease III is a Mg-dependent 3' to 5' exonuclease acting on dsDNA, which releases 5' phosphomononucleotides as degradation products

Date:: 2023-03-03

Family Accession:: 10013876
Method:: Sparcle

Select item 218675.

exodeoxyribonuclease III

All proteins in this family for which functions are known are 5' AP endonucleases that function in base excision repair and the repair of abasic sites in DNA. Note that the member from Methanothermobacter thermautotrophicus functions additionally as a DNA uridine endonuclease. This family derived from the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).

GO Terms:

Molecular Function:: nuclease activity (GO:0004518)

Biological Process:: DNA repair (GO:0006281)

Date:: 2024-05-30

Family Accession:: TIGR00633.1
Method:: HMM

Select item 164346.

exodeoxyribonuclease III

The model brings in reverse transcriptases at scores below 50, model also contains eukaryotic apurinic/apyrimidinic endonucleases which group in the same family