Protein Family Models for Gene (Select 89453468) - Protein Family Models

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Items: 3

Select item 3881961.

new record, indexing in progress

Family Accession:

Select item 3464372.

new record, indexing in progress

Family Accession:

Select item 1427503.

ornithine--oxo-acid transaminase

This HMM describes the final step in the biosynthesis of ornithine from glutamate via the non-acetylated pathway. Ornithine amino transferase takes L-glutamate 5-semialdehyde and makes it into ornithine, which is used in the urea cycle, as well as in the biosynthesis of arginine. This model includes low-GC bacteria and eukaryotic species. The genes from two species are annotated as putative acetylornithine aminotransferases - one from Porphyromonas gingivalis (OMNI|PG1271), and the other from Staphylococcus aureus (OMNI|SA0170). After homology searching using BLAST it was determined that these two sequences were most closely related to ornithine aminotransferases. This model's seed includes one characterized hit, from Bacillus subtilis (SP|P38021).