Protein Family Models for Gene (Select 89570791) - Protein Family Models

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Items: 8

Select item 3955651.

new record, indexing in progress

Family Accession:

Select item 3899642.

new record, indexing in progress

Family Accession:

Select item 3579533.

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Family Accession:

Select item 3468694.

new record, indexing in progress

Family Accession:

Select item 2268905.

2-isopropylmalate synthase

2-isopropylmalate synthase converts acetyl-CoA and alpha-ketoisovalerate into alpha-isopropylmalate in the committed step of leucine biosynthesis

Date:: 2023-03-02

Family Accession:: 11479332
Method:: Sparcle

Select item 1770386.

2-isopropylmalate synthase

GO Terms:

Molecular Function:: 2-isopropylmalate synthase activity (GO:0003852)

Biological Process:: L-leucine biosynthetic process (GO:0009098)

Biological Process:: carboxylic acid metabolic process (GO:0019752)

Date:: 2021-08-23

Family Accession:: NF002086.0
Method:: HMM

Select item 1762407.

2-isopropylmalate synthase

GO Terms:

Molecular Function:: 2-isopropylmalate synthase activity (GO:0003852)

Date:: 2021-08-12

Family Accession:: NF002087.0
Method:: HMM

Select item 245388.

2-isopropylmalate synthase

This is the first enzyme of leucine biosynthesis. A larger family of homologous proteins includes homocitrate synthase, distinct lineages of 2-isopropylmalate synthase, several distinct, uncharacterized, orthologous sets in the Archaea, and other related enzymes. This model describes a family of 2-isopropylmalate synthases found primarily in Bacteria. The homologous families in the Archaea may represent isozymes and/or related enzymes.