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Items: 6

1.
new record, indexing in progress
Family Accession:
2.
new record, indexing in progress
Family Accession:
3.
new record, indexing in progress
Family Accession:
4.

formyltetrahydrofolate deformylase

formyltetrahydrofolate deformylase catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to tetrahydrofolate (FH4) and formate

Date:
2023-03-17
Family Accession:
11481955
Method:
Sparcle
5.

formyltetrahydrofolate deformylase

Produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine

Date:
2020-10-26
Family Accession:
NF004684.0
Method:
HMM
6.

formyltetrahydrofolate deformylase

This HMM describes formyltetrahydrofolate deformylases. The enzyme is a homohexamer. Sequences from a related enzyme formyl tetrahydrofolate-specific enzyme, phosphoribosylglycinamide formyltransferase, serve as an outgroup for phylogenetic analysis. Putative members of this family, scoring below the trusted cutoff, include a sequence from Rhodobacter capsulatus that lacks an otherwise conserved C-terminal region.

Gene:
purU
GO Terms:
Biological Process:
'de novo' IMP biosynthetic process (GO:0006189)
Molecular Function:
formyltetrahydrofolate deformylase activity (GO:0008864)
Date:
2024-05-29
Family Accession:
TIGR00655.1
Method:
HMM
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