Protein Family Models for Protein (Select 1011725981) - Protein Family Models

Select item 4386341.

sigma-54 dependent transcriptional regulator

sigma-54-dependent transcriptional regulator containing a sigma-54 interaction domain

Date:: 2024-05-24

Family Accession:: 20556987
Method:: Sparcle

Select item 4271372.

The TyrR protein of Haemophilus influenzae is a 36-kD transcription factor whose major function is to control the expression of genes important in the biosynthesis and transport of aromatic amino acids [1]. This entry represents the C-terminal helix-turn-helix DNA-binding domain of TyrR and related proteins. [1]. 11344327. Solution structure of the DNA-binding domain of the TyrR protein of Haemophilus influenzae. Wang Y, Zhao S, Somerville RL, Jardetzky O;. Protein Sci. 2001;10:592-598. (from Pfam)

GO Terms:

Molecular Function:: DNA binding (GO:0003677)

Date:: 2024-10-16

Family Accession:: NF036547.5
Method:: HMM

Select item 4244403.

Sigma-54 interaction domain

GO Terms:

Molecular Function:: ATP binding (GO:0005524)

Biological Process:: regulation of DNA-templated transcription (GO:0006355)

Molecular Function:: transcription factor binding (GO:0008134)

Date:: 2024-08-14

Family Accession:: NF025885.5
Method:: HMM

Select item 4172424.

Flagellar regulatory protein FleQ

This domain is found at the N terminus of a subset of sigma54-dependent transcriptional activators that are involved in regulation of flagellar motility e.g. FleQ in Pseudomonas aeruginosa. It is clearly related to Pfam:PF00072, but lacks the conserved aspartate residue that undergoes phosphorylation in the classic two-component system response regulator (Pfam:PF00072). [1]. 12218010. FleQ, the major flagellar gene regulator in Pseudomonas aeruginosa, binds to enhancer sites located either upstream or atypically downstream of the RpoN binding site. Jyot J, Dasgupta N, Ramphal R;. J Bacteriol 2002;184:5251-5260. [2]. 11673434. Interaction of the antiactivator FleN with the transcriptional activator FleQ regulates flagellar number in Pseudomonas aeruginosa. Dasgupta N, Ramphal R;. J Bacteriol 2001;183:6636-6644. [3]. 10629180. fleN, a gene that regulates flagellar number in Pseudomonas aeruginosa. Dasgupta N, Arora SK, Ramphal R;. J Bacteriol 2000;182:357-364. [4]. 12618438. Domain Architectures of sigma(54)-Dependent Transcriptional Activators. Studholme DJ, Dixon R;. J Bacteriol 2003;185:1757-1767. (from Pfam)

Date:: 2024-10-16

Family Accession:: NF018228.5
Method:: HMM

Select item 4169355.

AAA family ATPase

This Pfam entry includes some of the AAA proteins not detected by the Pfam:PF00004 model. [1]. 7646486. A 200-amino acid ATPase module in search of a basic function. Confalonieri F, Duguet M;. Bioessays 1995;17:639-650. A large extension of the family. [2]. 9927482. AAA+: A class of chaperone-like ATPases associated with the assembly, operation, and disassembly of protein complexes. Neuwald AF, Aravind L, Spouge JL, Koonin EV;. Genome Res 1999;9:27-43. (from Pfam)

GO Terms:

Molecular Function:: ATP binding (GO:0005524)

Molecular Function:: ATP hydrolysis activity (GO:0016887)

Date:: 2024-10-16

Family Accession:: NF019348.5
Method:: HMM

Select item 4128936.

helix-turn-helix domain-containing protein

GO Terms:

Molecular Function:: sequence-specific DNA binding (GO:0043565)

Date:: 2024-08-14

Family Accession:: NF014950.5
Method:: HMM

Select item 4118797.

sigma 54-interacting transcriptional regulator

GO Terms:

Molecular Function:: ATP binding (GO:0005524)

Biological Process:: regulation of DNA-templated transcription (GO:0006355)

Molecular Function:: transcription factor binding (GO:0008134)

Date:: 2024-08-14

Family Accession:: NF012385.5
Method:: HMM

Select item 4037128.