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type-F conjugative transfer system secretin TraK
This family consists of several TraK proteins from Escherichia coli, Salmonella typhi and Salmonella typhimurium. TraK is known to be essential for pilus assembly but its exact role in this process is unknown [1]. [1]. 8655498. Analysis of the traLEKBP sequence and the TraP protein from three F-like plasmids: F, R100-1 and ColB2. Anthony KG, Kathir P, Moore D, Ippen-Ihler K, Frost LS;. J Bacteriol 1996;178:3194-3200. (from Pfam)
type-F conjugative transfer system secretin TraK is involved in pilus assembly
The TraK protein is predicted to interact with the TraV and TraB proteins as part of the scaffold which extends from the inner membrane, through the periplasm to the cell envelope and through which the F-type conjugative pilus passes. TraK is homologous to the P-type IV secretion system protein TrbG, the Ti-type protein VirB9 and the I-type TraN protein. The protein is related to the secretin family especially the HrcC subgroup of the type III secretion system. The protein is hypothesized to oligomerize to form a ring structure akin to other secretins [1,2,3].
F-type conjugal transfer protein TraK
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